I fitted a mixed-effects model with a Variance Structure in nlme
(because Variance Structures are not yet implemented in lme4). After
several model fittings (with method="ML"), I found the optimal fixed
structure of my explanatory variables. 

I understood from this mailing list that the p-values of the fixed
effects, given by summary(namemodel) are not trustable and thus I want
to use a Monte Carlo simulation in order to estimate the significance of
the fixed terms. This command doesn't exist in nlme, and I can't fit my
model in lme4. Is there a way to overcome this problem? Or another
function in nlme that gives comparable results?

 

 

Thanks a lot,

Sebastiaan

 

Sebastiaan De Smedt

Research assistant

UA - Department of Bioscience Engineering

 

Groenenborgerlaan 171 - V6.16

B-2020 Antwerpen, Belgium

+32 (0)3 265 34 51

 

 


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