[R-sig-ME] Confidence interval around random effect variances in place of p-value

Ben Bolker bbo|ker @end|ng |rom gm@||@com
Mon Apr 5 00:58:10 CEST 2021


   This would make an interesting simulation and/or theoretical exercise 
(I'm going to resist the urge to do it), i.e. identifying the 
correspondence between p-values constructed from parametric bootstrap 
full-vs-reduced model comparisons and p-values estimated as fraction of 
PB fits of full model that give variance=0 for the tested variance 
component(s).

On 4/2/21 8:22 PM, Jack Solomon wrote:
> Well, how about concluding so:
> 
> If a (say 2-level) model gives a singular fit (even though perhaps there 
> is a "tol" that is small but not exactly "0" for that warning to show 
> up), that would mean we have a "practically" non-significant 
> random-effect variance component.
> 
> 
> 
> On Fri, Apr 2, 2021 at 7:15 PM Ben Bolker <bbolker using gmail.com 
> <mailto:bbolker using gmail.com>> wrote:
> 
>          I'm not sure that the bootstrapped CIs *wouldn't* work; they might
>     return the correct proportion of singular fits ...
> 
>     On 4/2/21 8:12 PM, Jack Solomon wrote:
>      > Thank you all very much. So, I can conclude that a likelihood
>     ratio test
>      > and/or a parametric bootstrapping can be used for random effect
>     variance
>      > component hypothesis testing.
>      >
>      > But I also concluded that the idea of simply using a bootstrapped
>     CI for
>      > a random-effect variance component [e.g., in lme4;
>      > confint(model,method="boot",oldNames=FALSE)  ] by definition
>     can't be
>      > used for significance testing, because it requires the
>     possibility of
>      > seeing sd = 0 which can't be "strictly" captured by such a CI from a
>      > multilevel model (at least not easily so).
>      >
>      > I hope my conclusions are correct,
>      > Thank you all, Jack
>      >
>      > On Fri, Apr 2, 2021 at 6:51 PM Ben Bolker <bbolker using gmail.com
>     <mailto:bbolker using gmail.com>
>      > <mailto:bbolker using gmail.com <mailto:bbolker using gmail.com>>> wrote:
>      >
>      >        Sure. If all you want is p-values, I'd recommend parametric
>      >     bootstrapping (implemented in the pbkrtest package) ... that
>     will avoid
>      >     these difficulties.  (I would also make sure that you know
>     *why* you
>      >     want p-values on the random effects ... they have all of the
>     issues of
>      >     regular p-values plus some extras:
>      >
>     http://bbolker.github.io/mixedmodels-misc/glmmFAQ.html#testing-significance-of-random-effects
>     <http://bbolker.github.io/mixedmodels-misc/glmmFAQ.html#testing-significance-of-random-effects>
>      >   
>       <http://bbolker.github.io/mixedmodels-misc/glmmFAQ.html#testing-significance-of-random-effects <http://bbolker.github.io/mixedmodels-misc/glmmFAQ.html#testing-significance-of-random-effects>>
>      >
>      >     )
>      >
>      >     On 4/2/21 7:37 PM, Jack Solomon wrote:
>      >      > Thanks. Just to make sure, to declare a statistically
>      >     NON-significant
>      >      > random effect variance component, the lower bound of the
>     CI must be
>      >      > EXACTLY "0", right?
>      >      >
>      >      > Tha is, for example, a CI like: [.0002, .14] is a
>      >      > statistically significant random-effect variance component but
>      >     one that
>      >      > perhaps borders a p-value of relatively close to but
>     smaller than
>      >     .05,
>      >      > right?
>      >      >
>      >      > On Fri, Apr 2, 2021 at 6:19 PM Ben Bolker
>     <bbolker using gmail.com <mailto:bbolker using gmail.com>
>      >     <mailto:bbolker using gmail.com <mailto:bbolker using gmail.com>>
>      >      > <mailto:bbolker using gmail.com <mailto:bbolker using gmail.com>
>     <mailto:bbolker using gmail.com <mailto:bbolker using gmail.com>>>> wrote:
>      >      >
>      >      >         This seems like a potential can of worms (as
>     indeed are all
>      >      >     hypothesis tests of null values on a boundary ...)
>     However,
>      >     in this
>      >      >     case
>      >      >     bootstrapping (provided you have resampled appropriately -
>      >     you may need
>      >      >     to do hierarchical bootstrapping ...) seems reasonable,
>      >     because a null
>      >      >     model would give you singular fits (i.e. estimated
>     sd=0) half
>      >     of the
>      >      >     time ...
>      >      >
>      >      >         Happy to hear more informed opinions.
>      >      >
>      >      >     On 4/2/21 6:55 PM, Jack Solomon wrote:
>      >      >      > Dear All,
>      >      >      >
>      >      >      > A colleague of mine suggested that I use the
>     bootstrapped CIs
>      >      >     around my
>      >      >      > model's random effect variances in place of
>     p-values for them.
>      >      >      >
>      >      >      > But random effect variances (or sds) start from
>     "0". So,
>      >     to declare a
>      >      >      > statistically NON-significant random effect variance
>      >     component, the
>      >      >      > lower bound of the CI must be EXACTLY "0", right?
>      >      >      >
>      >      >      > Thank you very much,
>      >      >      > Jack
>      >      >      >
>      >      >      >       [[alternative HTML version deleted]]
>      >      >      >
>      >      >      > _______________________________________________
>      >      >      > R-sig-mixed-models using r-project.org
>     <mailto:R-sig-mixed-models using r-project.org>
>      >     <mailto:R-sig-mixed-models using r-project.org
>     <mailto:R-sig-mixed-models using r-project.org>>
>      >      >     <mailto:R-sig-mixed-models using r-project.org
>     <mailto:R-sig-mixed-models using r-project.org>
>      >     <mailto:R-sig-mixed-models using r-project.org
>     <mailto:R-sig-mixed-models using r-project.org>>> mailing list
>      >      >      >
>     https://stat.ethz.ch/mailman/listinfo/r-sig-mixed-models
>     <https://stat.ethz.ch/mailman/listinfo/r-sig-mixed-models>
>      >     <https://stat.ethz.ch/mailman/listinfo/r-sig-mixed-models
>     <https://stat.ethz.ch/mailman/listinfo/r-sig-mixed-models>>
>      >      >   
>       <https://stat.ethz.ch/mailman/listinfo/r-sig-mixed-models
>     <https://stat.ethz.ch/mailman/listinfo/r-sig-mixed-models>
>      >     <https://stat.ethz.ch/mailman/listinfo/r-sig-mixed-models
>     <https://stat.ethz.ch/mailman/listinfo/r-sig-mixed-models>>>
>      >      >      >
>      >      >
>      >      >     _______________________________________________
>      >      > R-sig-mixed-models using r-project.org
>     <mailto:R-sig-mixed-models using r-project.org>
>      >     <mailto:R-sig-mixed-models using r-project.org
>     <mailto:R-sig-mixed-models using r-project.org>>
>      >      >     <mailto:R-sig-mixed-models using r-project.org
>     <mailto:R-sig-mixed-models using r-project.org>
>      >     <mailto:R-sig-mixed-models using r-project.org
>     <mailto:R-sig-mixed-models using r-project.org>>> mailing list
>      >      > https://stat.ethz.ch/mailman/listinfo/r-sig-mixed-models
>     <https://stat.ethz.ch/mailman/listinfo/r-sig-mixed-models>
>      >     <https://stat.ethz.ch/mailman/listinfo/r-sig-mixed-models
>     <https://stat.ethz.ch/mailman/listinfo/r-sig-mixed-models>>
>      >      >   
>       <https://stat.ethz.ch/mailman/listinfo/r-sig-mixed-models
>     <https://stat.ethz.ch/mailman/listinfo/r-sig-mixed-models>
>      >     <https://stat.ethz.ch/mailman/listinfo/r-sig-mixed-models
>     <https://stat.ethz.ch/mailman/listinfo/r-sig-mixed-models>>>
>      >      >
>      >
>



More information about the R-sig-mixed-models mailing list