[R-sig-ME] Performing a single animal model that estimates additive genetic variation for many populations?

[David Duffy]

On Thu, 18 Jun 2015, Jackie Wood wrote:

> I'm working on a manuscript which investigates the relationship of various
> metrics of adaptive potential (additive genetic variation (VA),
> heritability (h2), and mean-scaled evolvability (IA)) with population size
> in a common garden experiment using a large number of wild, isolated
> populations of a vertebrate fish. One comment/request we received on the
> manuscript was whether we could fit a single animal model that includes all
> of our populations. That is, in addition to the standard terms to estimate
> VA, whether we could also include population size and interactions with
> population size such that we could examine whether VA (or h2 or IA) varies
> among populations, and the magnitude of the interaction between population
> and additive (and potentially maternal) effects.
>

Yes ;) It is essentially a GxE term. Probably MCMCglmm would be easiest.


| David Duffy (MBBS PhD)
| email: David.Duffy at qimrberghofer.edu.au  ph: INT+61+7+3362-0217 fax: -0101
| Genetic Epidemiology, QIMR Berghofer Institute of Medical Research
| 300 Herston Rd, Brisbane, Queensland 4006, Australia  GPG 4D0B994A