[R-sig-ME] c++ exception with logistic glmer

David Duffy David.Duffy at qimr.edu.au
Thu Jan 8 06:32:16 CET 2015

On Tue, 6 Jan 2015, Cole, Tim wrote:

> I'm returning to a thread I started a year ago. My logistic glmer model
> and Jonathan French and Ben suggested an alternative time-to-event 
> analysis instead of the logistic.

As now described, your problem is clearly interval censored time-to-event, 
and your logistic model is just not the right approach - bone maturity is 
an irreversible state (consider what happens to your age regression 
coefficient if you add in more ages before or after maturity).  Either do 
the survival analysis, which gives you the median age at maturity, or fit 
a (nonlinear) growth model to maturity score.

| David Duffy (MBBS PhD)
| email: David.Duffy at qimrberghofer.edu.au  ph: INT+61+7+3362-0217 fax: -0101
| Genetic Epidemiology, QIMR Berghofer Institute of Medical Research
| 300 Herston Rd, Brisbane, Queensland 4006, Australia  GPG 4D0B994A

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