[R-sig-ME] Issue with experimental design?

[Ted Wright]

You should treat this as a 3-group design. There is no nesting or crossing,
but you can still compare the outcomes for the three groups.

Ted Wright

-----Original Message-----
From: r-sig-mixed-models-bounces at r-project.org
[mailto:r-sig-mixed-models-bounces at r-project.org] On Behalf Of Yla Savh
Sent: Saturday, October 12, 2013 4:11 AM
To: r-sig-mixed-models at r-project.org
Subject: [R-sig-ME] Issue with experimental design?

Dear forum members, Could you please help me confirm if there is a problem
with the experimental design? There are two initial groups (vitamin D
deficient and normal group). Then, the D deficient group has two treatments
(with a low D dosage and a high D dosage), while the normal group has only
one treatment (maintenance therapy). 
Initially, I thought it might be a nested design (treatment nested within
groups, where the treatment is a fixed effect, and groups and treatment
nested in groups are random effects. However, I do not think it is a correct
design as the groups did not include the same treatments. Am I correct?
I see only one solution where we will have only one or two groups and the
same treatments should apply to each of them. Are there other
solutions?Thanks,Julia

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