[R-sig-ME] Is BLUP a good thing?
David Duffy
davidD at qimr.edu.au
Mon Mar 28 07:19:00 CEST 2011
On Mon, 28 Mar 2011, Dominick Samperi wrote:
> After reading the recent publications on the dangers of applying BLUP to
> natural populations (Hadfield et al 2010, Morrissey et al 2010) I was
> left wondering why it works at all. The latter paper claims that BLUP
> has a long and successful history when applied to animal breeding,
> but no examples showing its effectiveness were presented.
It depends on how much additional information your model for the latent
variables carries. In the genetic case, you have a strong biological
model for the genetic covariances between individuals given the
relationships, and in the animal breeding case, lots of data (eg milk
production in hundreds of offspring of a single prize bull).
Other usages are to give shrunken estimators in an empirical Bayes way,
but for frequentists ;), or disattenuation of measurement error, or
estimation of factor scores (they may not actually be called BLUPs in
other fields).
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