[R-sig-ME] Another case of -1.0 correlation of random effects
Ken Knoblauch
ken.knoblauch at inserm.fr
Fri Apr 9 16:15:13 CEST 2010
Yes. It was a knee-jerk reaction, recalling a trap that
I fell into before with glm. But, lmer seems to handle
this smoothly for the grouping factor. Thanks.
Ken
Quoting Ben Bolker <bolker at ufl.edu>:
> Ken Knoblauch wrote:
>> Kevin E. Thorpe <kevin.thorpe at ...> writes:
>>
>>> My data come from a crossover trial and are balanced.
>>>
>>> > str(gluc)
>>> 'data.frame': 96 obs. of 4 variables:
>>> $ Subject : int 1 2 3 5 6 7 10 11 12 13 ...
>>> $ Treatment: Factor w/ 2 levels "Barley","Oat": 1 1 1 1 1 1 1 1 1 1 ...
>>> $ Dose : int 8 8 8 8 8 8 8 8 8 8 ...
>>> $ iAUC : num 110 256 129 207 244 ...
>>>
>>
>>> clip>
>>
>> Shouldn't you make Subject into a factor?
>>
>> Ken
>>
>
> It would make the plot a little bit prettier but I don't think it
> matters in this case because variable that appears as a grouping
> variable (i.e. on the right of the | ) is automatically treated as a
> factor? I think?
>
> Since it is really a crossover trial, it would seem reasonable in
> principle to have the (Treatment|Subject) random effect in there as
> well. I'm not sure what to do about the -1 correlation: it seems the
> choices (not necessarily in order) are (1) throw up your hands and say
> there's not enough data to estimate independently; (2) try WinBUGS,
> possibly with slightly informative priors; (3) try using lme4a to create
> profiles of the parameters and see if you can figure out what's happening.
>
>
>
> --
> Ben Bolker
> Associate professor, Biology Dep't, Univ. of Florida
> bolker at ufl.edu / people.biology.ufl.edu/bolker
> GPG key: people.biology.ufl.edu/bolker/benbolker-publickey.asc
>
--
Ken Knoblauch
Inserm U846
Stem-cell and Brain Research Institute
Department of Integrative Neurosciences
18 avenue du Doyen Lépine
69500 Bron
France
tel: +33 (0)4 72 91 34 77
fax: +33 (0)4 72 91 34 61
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http://www.sbri.fr/members/kenneth-knoblauch.html
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