[R-sig-ME] 'adjusting for bias' in a Poisson model
bolker at ufl.edu
Sat Jan 3 16:23:26 CET 2009
"offset" is you want to look for.
offsets apply on the scale of the linear predictor
(log scale in this case), so I think adding something
like offset=((x==1)*log(0.8)) to the model will do
Henrik Parn wrote:
> Dear all,
> Basically, I have fitted a mixed model with poisson error to analyse how
> number of offspring (y) depend on a fixed factor (x). The data is
> grouped by two random factors (gr1, gr2).
> # Some test data with at least a similar structure:
> test.data <- data.frame(
> y = c(rpois(40, 5.5), rpois(40, 3.5)),
> x = factor(rep(0:1, each = 40)),
> gr1 = factor(rep(1:4, each = 10)),
> gr2 = factor(rep(1:2, each = 5)))
> # The model
> model <- lmer(y ~ x + (1|gr1) + (1|gr2),
> data = test.data, family = poisson)
> Generalized linear mixed model fit by the Laplace approximation
> Formula: y ~ x + (1 | gr1) + (1 | gr2)
> Data: test.data
> AIC BIC logLik deviance
> 61.01 70.54 -26.51 53.01
> Random effects:
> Groups Name Variance Std.Dev.
> gr1 (Intercept) 0.00045437 0.021316
> gr2 (Intercept) 0.00000000 0.000000
> Number of obs: 80, groups: gr1, 4; gr2, 2
> Fixed effects:
> Estimate Std. Error z value Pr(>|z|)
> (Intercept) 1.75331 0.06666 26.302 < 2e-16 ***
> x1 -0.48660 0.10665 -4.563 5.05e-06 ***
> Thus, y is significantly higher for x = 0 than for x = 1. However, it
> has been suggested that the estimate of x may be biased (for biological
> reasons) and actually be less negative than what is found above.
> Specifically, even in absence of an effect of x, the bias could cause y
> for x = 1 to be 20% lower than y for x = 0.
> (y for x=0 - y for x=1)/ y for x=0 = 20%; y for x=1 could be 0.8*y for
> x=0 due to bias.
> Thus, the estimate of x would be (1.75331 - 0.2 * 1.75331) - 1.75331 =
> -1.75331 * 0.2 = -0.350662 just due to the bias.
> I wish to test if there is an effect of x on y over and above the
> potential 20% bias.
> My naive starting point: Instead of testing if the estimate of x
> (-0.48660) differs from zero, I would need to test if -0.48660 -
> (-0.350662) = -0.135938 differs fro zero.
> Or could I somehow make the adjustment already in the data set, e.g.
> adjusting the y's for x = 1? But I assume that I cannot 'just add ?? %
> to y in group x', because the response has to be integers?
> Does anyone have a suggestion of a convenient way of performe test for
> significance of x on y while taking the bias into account?
> Thanks a lot in advance!
Associate professor, Biology Dep't, Univ. of Florida
bolker at ufl.edu / www.zoology.ufl.edu/bolker
GPG key: www.zoology.ufl.edu/bolker/benbolker-publickey.asc
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