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Dear Michael, </div>
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Thank you for your response. I did not apply any moderator for the pooled OR in the meta-analysis. Could you clarify something for me?</div>
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In a meta-analysis, is it always necessary to calculate the pooled OR including a moderator variable?</div>
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<b>Another question:</b></div>
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Was the pooled OR supposed to be significant in the following conde (image):</div>
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<img size="45154" contenttype="image/png" style="max-width: 1250px;" data-outlook-trace="F:1|T:1" src="cid:e86aae67-ad2a-4dec-a5f5-4a214aed2118"></div>
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<b>Results:</b></div>
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<img id="image_1" size="28385" contenttype="image/png" style="max-width: 1250px;" data-outlook-trace="F:1|T:1" src="cid:aca4f231-bf57-496a-893a-c1f29cf695eb"></div>
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<b>Dataset:</b></div>
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<b><img id="image_0" size="13388" contenttype="image/png" style="max-width: 1250px;" data-outlook-trace="F:1|T:1" src="cid:51413303-309e-44f9-b5db-e6de14dbf480"></b></div>
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<b><br>
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Do you have any suggestions, ideas, or observations about the scripts and results based on the dataset?</div>
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Best wishes,</div>
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<div style="font-size: 10pt;"><b>Sancho Xavier</b></div>
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Candidate for Postgraduate Programme in Epidemiology in Public Health</div>
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MBA in Data Science and Analytics at USP (ongoing)</div>
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<b>Linkedin:</b> linkedin.com/in/sancho-xavier-59565a18a</div>
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<b>Orcid iD:</b> https://orcid.org/0000-0001-9493-4098</div>
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<b>Web of Science (Clarivate):</b> <a href="https://www.webofscience.com/wos/author/record/GON-5675-2022">https://www.webofscience.com/wos/author/record/GON-5675-2022</a></div>
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<b>Reference Citation Analysis (RCA): </b><a href="https://referencecitationanalysis.com/00001471">https://referencecitationanalysis.com/00001471</a></div>
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<b>Whatsapp: </b>+258 852255846 </div>
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<div id="divRplyFwdMsg" dir="ltr"><font face="Calibri, sans-serif" style="font-size:11pt" color="#000000"><b>De:</b> Michael Dewey <lists@dewey.myzen.co.uk><br>
<b>Enviado:</b> quarta-feira, 31 de julho de 2024 05:05<br>
<b>Para:</b> R Special Interest Group for Meta-Analysis <r-sig-meta-analysis@r-project.org><br>
<b>Cc:</b> Sancho Xavier <sanchoxavierxavier@gmail.com><br>
<b>Assunto:</b> Re: [R-meta] Is this R script correct for conducting a meta-analysis of AOR for hypertension prevalence?</font>
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<div class="PlainText">Dear Sancho<br>
<br>
Are you intending to use the variable you have named variable as a <br>
moderator? If not the code looks fine to me although I do not usually <br>
use that package (I assume it is meta).<br>
<br>
Michael<br>
<br>
On 27/07/2024 00:18, Sancho Xavier via R-sig-meta-analysis wrote:<br>
> *Hi, community!*<br>
> I am conducting a meta-analysis and meta-regression to calculate the <br>
> */pooled adjusted odds ratio (AOR)/* and */IČ with the p-value/* for <br>
> variables associated with hypertension prevalence. I have a dataset with <br>
> the following columns:<br>
> <br>
> * *study_id:* Study identifier<br>
> * *AOR:* Adjusted odds ratio (each independent variable)<br>
> * *lower_CI:* Lower confidence interval (each independent variable)<br>
> * *upper_CI:* Upper confidence interval (each independent variable)<br>
> * *variable:* Independent variable<br>
> <br>
> Here is the script I am using in *R*:<br>
> <br>
> *# Calculate the standard error (seTE)*<br>
> *<br>
> *<br>
> data$seTE <- (log(data$upper_CI) - log(data$lower_CI)) / (2 * 1.96)<br>
> <br>
> *# Meta-analysis*<br>
> *<br>
> *<br>
> meta_analysis <- metagen(TE = log(data$AOR),<br>
> seTE = data$seTE,<br>
> data = data,<br>
> studlab = data$study_id,<br>
> comb.fixed = TRUE,<br>
> comb.random = TRUE)<br>
> <br>
> *I would like to know if this script is correct for achieving my goals of:*<br>
> <br>
> * Calculating the pooled AOR and the 95% confidence interval.<br>
> *<br>
> Calculating the IČ and the p-value to assess heterogeneity.<br>
> <br>
> Look at the dataset:<br>
> <br>
> Any feedback or suggestions for improvement would be greatly appreciated!<br>
> <br>
> Thank you!<br>
> <br>
> *Sancho Xavier*<br>
> Candidate for Postgraduate Programme in Epidemiology in Public Health<br>
> MBA in Data Science and Analytics at USP (ongoing)<br>
> *Linkedin:* linkedin.com/in/sancho-xavier-59565a18a<br>
> *Orcid iD:* <a href="https://orcid.org/0000-0001-9493-4098">https://orcid.org/0000-0001-9493-4098</a><br>
> *Web of Science (Clarivate):* <br>
> <a href="https://www.webofscience.com/wos/author/record/GON-5675-2022">https://www.webofscience.com/wos/author/record/GON-5675-2022</a>
<br>
> <<a href="https://www.webofscience.com/wos/author/record/GON-5675-2022">https://www.webofscience.com/wos/author/record/GON-5675-2022</a>><br>
> *Reference Citation Analysis (RCA): <br>
> *https://referencecitationanalysis.com/00001471 <br>
> <<a href="https://referencecitationanalysis.com/00001471">https://referencecitationanalysis.com/00001471</a>><br>
> *Whatsapp: *+258 852255846<br>
> ------------------------------------------------------------------------------<br>
> <br>
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-- <br>
Michael<br>
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