<div dir='auto'>Dear Wolfgang,<div dir="auto"><br></div><div dir="auto">thank you very much! I subscribed to the list immediatly! </div><div dir="auto"><br></div><div dir="auto">Regards </div><div dir="auto">Tobias</div></div><div class="gmail_extra"><br><div class="gmail_quote">Am 07.10.2020 17:05 schrieb "Viechtbauer, Wolfgang (SP) " <wolfgang.viechtbauer@maastrichtuniversity.nl>:<br type="attribution" /><blockquote class="quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><p dir="ltr">Dear Tobis,
<br>
<br>
Please register to post to the mailing list.
<br>
<br>
As for your question: Yes, metafor can in principle do this. You would have to combine methods from these examples:
<br>
<br>
https://wviechtb.github.io/metafor/reference/dat.fine1993.html
<br>
https://wviechtb.github.io/metafor/reference/dat.ishak2007.html
<br>
<br>
(which deal with multiple estimates from the same study/group over time) with methods from these examples:
<br>
<br>
https://wviechtb.github.io/metafor/reference/dat.hasselblad1998.html
<br>
https://wviechtb.github.io/metafor/reference/dat.senn2013.html
<br>
<br>
(which are examples of network MAs).
<br>
<br>
I do not have any concrete examples to illustrate this though.
<br>
<br>
You could also look into these articles:
<br>
<br>
Dakin, H. A., Welton, N. J., Ades, A. E., Collins, S., Orme, M., & Kelly, S. (2011). Mixed treatment comparison of repeated measurements of a continuous endpoint: An example using topical treatments for primary open-angle glaucoma and ocular hypertension. Statistics in Medicine, 30(20), 2511-2535.
<br>
<br>
Ding, Y., & Fu, H. (2013). Bayesian indirect and mixed treatment comparisons across longitudinal time points. Statistics in Medicine, 32(15), 2613-2628.
<br>
<br>
Jansen, J. P., Vieira, M. C., & Cope, S. (2015). Network meta-analysis of longitudinal data using fractional polynomials. Statistics in Medicine, 34(15), 2294-2311.
<br>
<br>
They might provide code/examples. I think all of them use a Bayesian framework for model fitting.
<br>
<br>
Best,
<br>
Wolfgang
<br>
<br>
>-----Original Message-----
<br>
>From: R-sig-meta-analysis [mailto:r-sig-meta-analysis-bounces@r-project.org]
<br>
>On Behalf Of t.saueressig@gmx.de
<br>
>Sent: Wednesday, 07 October, 2020 16:33
<br>
>To: r-sig-meta-analysis@r-project.org
<br>
>Subject: [R-meta] Network Meta Analysis with multiple Time points
<br>
>
<br>
>Hello All,
<br>
>
<br>
>I have question concerning a network Meta analysis that contains studies
<br>
>which measure their results at multiple time points. Which package can deal
<br>
>with this sort of Data? I know metafor can handle multiple time points in
<br>
>pairwise MA via multivariate methods. So it is probably possible to do that
<br>
>too? Are there any examples how to do that?
<br>
>
<br>
>Regards
<br>
>
<br>
>Tobias
<br>
</p>
</blockquote></div><br></div>