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    <p>Dear Martin,</p>
    <p><br>
    </p>
    <p>one cannot conclude from the variances of pre/post values on the
      variance of the pre-post difference without knowing/making
      assumptions about the correkation.</p>
    <p><br>
    </p>
    <p>See the attached R code for a hypothetical example.</p>
    <p><br>
    </p>
    <p>Best,</p>
    <p>Gerta<br>
    </p>
    <p><br>
    </p>
    <p><br>
    </p>
    <div class="moz-cite-prefix">Am 07.11.2019 um 16:52 schrieb Martin
      Lobo:<br>
    </div>
    <blockquote type="cite"
cite="mid:MN2PR20MB2814B43C0CEFC61C3A8F89A1AC780@MN2PR20MB2814.namprd20.prod.outlook.com">
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        Thank you very much !!</div>
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        Do you know any method to impute the standard deviation of a
        difference of means (that is, I have the mean 1 with its
        deviation and the mean 2 with its deviation, I need to estimate
        the deviation of m1-m2)<br>
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        Best</div>
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                    font-family:Calibri,Helvetica,sans-serif,EmojiFont,"Apple
                    Color Emoji","Segoe UI
                    Emoji",NotoColorEmoji,"Segoe UI
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                    style="line-height:16.05px; color:rgb(38,114,236)"><font
                      size="5"><br>
                    </font></span></i></b></font></div>
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            <font face="Courier New"><b><i><span
                    style="line-height:16.05px; color:rgb(38,114,236)"><font
                      size="5">Lorenzo Martín Lobo </font></span></i></b></font><font
              face="Courier New"><b><i><sup><span
                      style="line-height:13.375px;
                      color:rgb(38,114,236)"><font size="1">MTSAC, FACC,
                        FESC</font></span></sup></i></b></font><br>
          </div>
          <div style="color:rgb(33,33,33);
            font-family:Calibri,Arial,Helvetica,sans-serif;
            font-size:15px">
            <font style="font-size:12pt"><i style="font-size:12pt"><font
                  face="Garamond"><b>Especialista Jerarquizado en
                    Cardiología</b></font></i></font></div>
          <div style="color:rgb(33,33,33);
            font-family:Calibri,Arial,Helvetica,sans-serif;
            font-size:15px">
            <font style="font-size:12pt"><i style="font-size:12pt"><font
                  face="Garamond"><b><font
                      style="font-family:Calibri,Arial,Helvetica,sans-serif;
                      font-style:normal; font-weight:400;
                      background-color:rgb(255,255,255); font-size:12pt"><i><font
                          face="Garamond"><b>Jefe de Cardiología </b></font></i></font><i
style="font-family:Calibri,Arial,Helvetica,sans-serif; font-size:12pt"><font
                        face="Garamond"><b>Hospital Militar Campo de
                          Mayo</b></font></i><br>
                  </b></font></i></font></div>
          <div style="color:rgb(33,33,33);
            font-family:Calibri,Arial,Helvetica,sans-serif;
            font-size:15px">
            <font style="font-size:12pt"><i style="font-size:12pt"><font
                  face="Garamond"><b>Ex Jefe de Unidad Coronaria </b></font></i></font><i
              style="font-size:12pt; font-variant-ligatures:inherit;
              font-variant-caps:inherit; font-weight:inherit"><font
                face="Garamond"><b>Hospital Militar Campo de Mayo</b></font></i></div>
          <div style="color:rgb(33,33,33);
            font-family:Calibri,Arial,Helvetica,sans-serif;
            font-size:15px">
            <font style="font-size:12pt"><i style="font-size:12pt">
                <div style="display:inline!important"><i
                    style="font-size:12pt"><font face="Garamond"><b>Miembro
                        Titular de la Sociedad Argentina de Cardiología</b></font></i></div>
              </i></font></div>
          <div style="color:rgb(33,33,33);
            font-family:Calibri,Arial,Helvetica,sans-serif;
            font-size:15px">
            <font style="font-size:12pt"><i style="font-size:12pt">
                <div style="display:inline!important"><i
                    style="font-size:12pt"><font face="Garamond"><b>Fellow
                        American College of Cardiology</b></font></i></div>
              </i></font></div>
          <div style="color:rgb(33,33,33);
            font-family:Calibri,Arial,Helvetica,sans-serif;
            font-size:15px">
            <font style="font-size:12pt"><i style="font-size:12pt">
                <div style="display:inline!important"><i
                    style="font-size:12pt"><font face="Garamond"><b>Fellow
                        European Society of Cardiology</b></font></i></div>
              </i></font></div>
          <div style="color:rgb(33,33,33);
            font-family:Calibri,Arial,Helvetica,sans-serif;
            font-size:15px">
            <font style="font-size:12pt"><i style="font-size:12pt">
                <div style="display:inline!important"><i
                    style="font-size:12pt"><font face="Garamond"><b><i
                          style="color:rgb(33,33,33);
                          font-family:Calibri,Arial,Helvetica,sans-serif;
                          font-size:12pt"><font face="Garamond"><b>Miembro
                              del Area de Investigación de la SAC</b></font></i></b></font></i></div>
              </i></font></div>
          <div style="color:rgb(33,33,33);
            font-family:Calibri,Arial,Helvetica,sans-serif;
            font-size:15px">
            <font style="font-size:12pt"><i style="font-size:12pt"><font
                  face="Garamond"><b>Ex Director del Consejo de
                    Aterosclerosis y Trombosis de la SAC</b></font></i></font></div>
          <div style="color:rgb(33,33,33);
            font-family:Calibri,Arial,Helvetica,sans-serif;
            font-size:15px">
            <font style="font-size:12pt"><i style="font-size:12pt"><font
                  face="Garamond"><b>Miembro Asesor <i
                      style="font-family:Calibri,Arial,Helvetica,sans-serif;
                      font-size:12pt; font-weight:400;
                      background-color:rgb(255,255,255)"><font
                        face="Garamond"><b>del Consejo de Aterosclerosis
                          y Trombosis de la SAC</b></font></i></b></font></i></font></div>
          <div style="color:rgb(33,33,33);
            font-family:Calibri,Arial,Helvetica,sans-serif;
            font-size:15px">
            <i style="font-size:12pt"><font face="Garamond"><b><i
                    style="font-family:Calibri,Arial,Helvetica,sans-serif,"Apple
                    Color Emoji","Segoe UI
                    Emoji",NotoColorEmoji,"Segoe UI
                    Symbol","Android Emoji",EmojiSymbols;
                    font-size:12pt">
                    <div style="display:inline!important"><i
                        style="font-size:12pt"><font face="Garamond"><b><i
style="font-family:Calibri,Arial,Helvetica,sans-serif; font-size:12pt">
                              <div style="display:inline!important"><i
                                  style="font-size:12pt"><font
                                    face="Garamond"><b>Ex Director del
                                      Consejo de Epidemiología y
                                      Prevención Cardiovascular de la
                                      SAC</b></font></i></div>
                            </i></b></font></i></div>
                  </i></b></font></i><br>
          </div>
          <div style="color:rgb(33,33,33);
            font-family:Calibri,Arial,Helvetica,sans-serif;
            font-size:15px">
            <i style="font-size:12pt"><font face="Garamond"><b><i
                    style="font-family:Calibri,Arial,Helvetica,sans-serif,"Apple
                    Color Emoji","Segoe UI
                    Emoji",NotoColorEmoji,"Segoe UI
                    Symbol","Android Emoji",EmojiSymbols;
                    font-size:12pt">
                    <div style="display:inline!important"><i
                        style="font-size:12pt"><font face="Garamond"><b><i
style="font-family:Calibri,Arial,Helvetica,sans-serif; font-size:12pt"><i
style="font-family:Calibri,Arial,Helvetica,sans-serif; font-weight:400;
                                background-color:rgb(255,255,255);
                                font-size:12pt"><font face="Garamond"><b><i
style="font-family:Calibri,Arial,Helvetica,sans-serif,"Apple Color
                                      Emoji","Segoe UI
                                      Emoji",NotoColorEmoji,"Segoe
                                      UI Symbol","Android
                                      Emoji",EmojiSymbols">
                                      <div style="margin:0px;
                                        display:inline!important"><i><font
                                            face="Garamond"><b><i
                                                style="font-family:Calibri,Arial,Helvetica,sans-serif">
                                                <div style="margin:0px;
display:inline!important"><i><font face="Garamond"><b>Miembro Asesor del
                                                        Consejo de
                                                        Epidemiología y
                                                        Prevención
                                                        Cardiovascular
                                                        de la SAC</b></font></i></div>
                                                <span> </span></i></b></font></i></div>
                                    </i></b></font></i><br>
                            </i></b></font></i></div>
                  </i></b></font></i></div>
          <div style="color:rgb(33,33,33);
            font-family:Calibri,Arial,Helvetica,sans-serif;
            font-size:15px">
            <font style="font-size:12pt"><i style="font-size:12pt">
                <div style="display:inline!important"><i
                    style="font-size:12pt"><font face="Garamond"><b>Instructor
                        de ACLS de la American Heart Association</b></font></i></div>
              </i></font></div>
          <br>
        </div>
        <div>
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            font-size:12pt; color:rgb(0,0,0)">
            <br>
          </div>
          <hr tabindex="-1" style="display:inline-block; width:98%">
          <div id="divRplyFwdMsg" dir="ltr"><font style="font-size:11pt"
              face="Calibri, sans-serif" color="#000000"><b>De:</b>
              Gerta Ruecker <a class="moz-txt-link-rfc2396E" href="mailto:ruecker@imbi.uni-freiburg.de"><ruecker@imbi.uni-freiburg.de></a><br>
              <b>Enviado:</b> jueves, 7 de noviembre de 2019 11:41<br>
              <b>Para:</b> Martin Lobo <a class="moz-txt-link-rfc2396E" href="mailto:mlobo4370@hotmail.com"><mlobo4370@hotmail.com></a>;
              Viechtbauer, Wolfgang (SP)
              <a class="moz-txt-link-rfc2396E" href="mailto:wolfgang.viechtbauer@maastrichtuniversity.nl"><wolfgang.viechtbauer@maastrichtuniversity.nl></a>;
              <a class="moz-txt-link-abbreviated" href="mailto:r-sig-meta-analysis@r-project.org">r-sig-meta-analysis@r-project.org</a>
              <a class="moz-txt-link-rfc2396E" href="mailto:r-sig-meta-analysis@r-project.org"><r-sig-meta-analysis@r-project.org></a><br>
              <b>Asunto:</b> Re: [R-meta] measurement conversion is
              possible ?</font>
            <div> </div>
          </div>
          <div style="background-color:#FFFFFF">
            <p>Dear Martin,</p>
            <p>There is some literature on this problem, see for example
              <a class="x_moz-txt-link-freetext"
href="https://eur04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fbmcmedresmethodol.biomedcentral.com%2Farticles%2F10.1186%2F1471-2288-14-135&data=02%7C01%7C%7C3f71f639d9a54095704708d763908f85%7C84df9e7fe9f640afb435aaaaaaaaaaaa%7C1%7C0%7C637087344854151219&sdata=nq0ylLfIqgDMCsXohvQw%2BqT2EARBTYUnUI%2F2%2FUUz7A4%3D&reserved=0"
originalsrc="https://bmcmedresmethodol.biomedcentral.com/articles/10.1186/1471-2288-14-135"
shash="ibMcUL7wNVcgWO2l98pyri33OVUsvQ8aATNKRdPAEN5tLdj+f9KLal3KLwHZfHZPN4qISw3pyYNmVbm9RcS++PQ+ShLodwt+r7eTDFrL5/4l9aZQ6TZpqffWLMl94XoOrx5eZboam8KSaJ3bfXjBOVgxhaiaNn8c2mOFCY3cFRc="
                moz-do-not-send="true">
https://bmcmedresmethodol.biomedcentral.com/articles/10.1186/1471-2288-14-135</a></p>
            <p>Best,</p>
            <p>Gerta<br>
            </p>
            <div class="x_moz-cite-prefix">Am 07.11.2019 um 15:27
              schrieb Martin Lobo:<br>
            </div>
            <blockquote type="cite">
              <pre class="x_moz-quote-pre">Hi everyones
Several times it happens that we do not have the measure we need or its dispersion.

for example:
median (inter quartile range)
median (confidence interval)
or we have mean (standard deviation) pre test and post test, but we don't have the standard deviation of the difference.
Is there any way with this data to estimate the mean and standard deviation without too much error (or that it is accepted methodologically)?

Thank you




Lorenzo Mart�n Lobo MTSAC, FACC, FESC
Especialista Jerarquizado en Cardiolog�a
Jefe de Cardiolog�a Hospital Militar Campo de Mayo
Ex Jefe de Unidad Coronaria Hospital Militar Campo de Mayo
Miembro Titular de la Sociedad Argentina de Cardiolog�a
Fellow American College of Cardiology
Fellow European Society of Cardiology
Miembro del Area de Investigaci�n de la SAC
Ex Director del Consejo de Aterosclerosis y Trombosis de la SAC
Miembro Asesor del Consejo de Aterosclerosis y Trombosis de la SAC
Ex Director del Consejo de Epidemiolog�a y Prevenci�n Cardiovascular de la SAC

Miembro Asesor del Consejo de Epidemiolog�a y Prevenci�n Cardiovascular de la SAC


Instructor de ACLS de la American Heart Association


________________________________
e la American Heart Association

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              <pre class="x_moz-quote-pre">_______________________________________________
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</pre>
            </blockquote>
            <pre class="x_moz-signature" cols="72">-- 

Dr. rer. nat. Gerta Rücker, Dipl.-Math.

Institute of Medical Biometry and Statistics,
Faculty of Medicine and Medical Center - University of Freiburg  

Stefan-Meier-Str. 26, D-79104 Freiburg, Germany

Phone:    +49/761/203-6673
Fax:      +49/761/203-6680
Mail:     <a class="x_moz-txt-link-abbreviated" href="mailto:ruecker@imbi.uni-freiburg.de" moz-do-not-send="true">ruecker@imbi.uni-freiburg.de</a>
Homepage: <a class="x_moz-txt-link-freetext" href="https://eur04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.imbi.uni-freiburg.de%2Fpersons%2Fruecker%2Fperson_view&data=02%7C01%7C%7C3f71f639d9a54095704708d763908f85%7C84df9e7fe9f640afb435aaaaaaaaaaaa%7C1%7C0%7C637087344854161231&sdata=dlwnYlxWB5q8qdYhfYv7keo4kNFHWXUz26jlcejUlhk%3D&reserved=0" originalsrc="https://www.imbi.uni-freiburg.de/persons/ruecker/person_view" shash="SYFd+v8p7Hvhjx2M3nbIbzk+ybS7r/xtr04ljLtkeGftz2ac0THPnK0vK18NqZ1/S2sQFyZjxV0tw5YtycgxL0FIelJFQM6blgTYuS2Twr3WAVLwvMCNjwQIakQL5GVrRvfTJ67u93tZvPuKNYcFB0ykEhZ3PwoCJWyCyZyMqyQ=" moz-do-not-send="true">https://www.imbi.uni-freiburg.de/persons/ruecker/person_view</a>
</pre>
          </div>
        </div>
      </div>
    </blockquote>
    <pre class="moz-signature" cols="72">-- 

Dr. rer. nat. Gerta Rücker, Dipl.-Math.

Institute of Medical Biometry and Statistics,
Faculty of Medicine and Medical Center - University of Freiburg  

Stefan-Meier-Str. 26, D-79104 Freiburg, Germany

Phone:    +49/761/203-6673
Fax:      +49/761/203-6680
Mail:     <a class="moz-txt-link-abbreviated" href="mailto:ruecker@imbi.uni-freiburg.de">ruecker@imbi.uni-freiburg.de</a>
Homepage: <a class="moz-txt-link-freetext" href="https://www.imbi.uni-freiburg.de/persons/ruecker/person_view">https://www.imbi.uni-freiburg.de/persons/ruecker/person_view</a>
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