<div dir="ltr"><div>Greetings everyone,<br></div><div><br></div><div>I am conducting my first network meta-analysis and for that I have been using netmeta. <br><br>I've
read a bit on general and network meta-analysis I can;t seem to find
any indication as to how to interpret the grey boxes or interval
demarcations that show up in netmeta's forest plots? <br><br><img src="cid:ii_15d8729e2ee8fbbb" alt="Inline image 1" width="480" height="480"><br><br>As
shown in the image above (can also be found in the attachments as
"forest.pl.jpeg"), these boxes appear to be plotted around some (or
perhaps all) of the model estimates. In some cases they also appear to
encompass an interval longer than the 95%CI intervals for the estimate
which is then shown in white instead of black ink. I was wondering what
type of interval was represented by these boxes and it was something
that was estimated for all treatments or only some of them?<br><br></div><div>In
addition, for a couple of the meta-analyses I am doing I have found
that the evidence networks are not well connected and end up as two
separate sub-networks. I was wondering whether it was appropriate to
conduct separate meta-analyses on the individual sub-networks or whether
there was any other way to try and tackle the analysis in these cases?<br><br></div><div>Thanks a lot for attention and any suggestions you can provide<div class="gmail-yj6qo gmail-ajU"><div id="gmail-:11o" class="gmail-ajR" tabindex="0"><span class="gmail-HOEnZb gmail-adL"></span><br><span class="gmail-HOEnZb gmail-adL"></span></div></div></div><span class="gmail-HOEnZb gmail-adL"><font color="#888888"><div>Carla</div></font></span></div><div class="gmail_extra"><br><div class="gmail_quote">On Fri, Jul 28, 2017 at 3:07 PM, Carla Gomez Creutzberg <span dir="ltr"><<a href="mailto:cgomezcre@gmail.com" target="_blank">cgomezcre@gmail.com</a>></span> wrote:<br><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><div dir="ltr"><div>Greetings everyone,<br></div><div><br></div><div>I am conducting my first network meta-analysis and for that I have been using netmeta. <br><br>I've read a bit on general and network meta-analysis I can;t seem to find any indication as to how to interpret the grey boxes or interval demarcations that show up in netmeta's forest plots? <br><br><img src="cid:ii_15d87291de6806bd" alt="Inline image 2" width="480" height="480"><br><br>As shown in the image above (can also be found in the attachments as "forest.pl.jpeg"), these boxes appear to be plotted around some (or perhaps all) of the model estimates. In some cases they also appear to encompass an interval longer than the 95%CI intervals for the estimate which is then shown in white instead of black ink. I was wondering what type of interval was represented by these boxes and it was something that was estimated for all treatments or only some of them?<br><br></div><div>In addition, for a couple of the meta-analyses I am doing I have found that the evidence networks are not well connected and end up as two separate sub-networks. I was wondering whether it was appropriate to conduct separate meta-analyses on the individual sub-networks or whether there was any other way to try and tackle the analysis in these cases?<br><br></div><div>Thanks a lot for attention and any suggestions you can provide<span class="HOEnZb"><font color="#888888"><div style="display:inline-block" id="m_-6468980779137928459gmail_4hwe5zru1sqv"></div><br><br></font></span></div><span class="HOEnZb"><font color="#888888"><div>Carla <br><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div><div> <br></div></div></div></div></div></div></div></div></div></div></div></div></div>
</div><div></div></font></span></div>
</blockquote></div><br><br clear="all"><br>-- <br><div class="gmail_signature" data-smartmail="gmail_signature"><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><b>Carla Gómez Creutzberg</b><br>
PhD. Candidate - <a href="http://www.tylianakislab.org/the-group.html" target="_blank">Tylianakis Lab</a><br>
University of Canterbury - <span lang="en-NZ"><font color="black" size="2" face="Tahoma"><span dir="ltr" style="font-size:10pt"><font size="2" face="Times New Roman"><span style="font-size:16px"><font size="2" face="Tahoma"><span style="font-size:10pt"><font size="1"><span style="font-size:13px"><font size="2"><i>Te
Whare Wānanga o Waitaha</i></font><font size="2"><i><br>
</i></font></span></font></span></font></span></font></span></font></span>Christchurch, New Zealand<a href="http://www.tylianakislab.org/the-group.html" target="_blank"></a> <br></div><div><a href="mailto:cgomezcre@gmail.com" target="_blank">cgomezcre@gmail.com</a> <br></div></div></div></div></div></div></div></div></div></div></div></div></div></div>
</div>