[R-meta] Is this R script correct for conducting a meta-analysis of AOR for hypertension prevalence?

Michael Dewey ||@t@ @end|ng |rom dewey@myzen@co@uk
Wed Jul 31 11:05:09 CEST 2024


Dear Sancho

Are you intending to use the variable you have named variable as a 
moderator? If not the code looks fine to me although I do not usually 
use that package (I assume it is meta).

Michael

On 27/07/2024 00:18, Sancho Xavier via R-sig-meta-analysis wrote:
> *Hi, community!*
> I am conducting a meta-analysis and meta-regression to calculate the 
> */pooled adjusted odds ratio (AOR)/* and */I² with the p-value/* for 
> variables associated with hypertension prevalence. I have a dataset with 
> the following columns:
> 
>   * *study_id:* Study identifier
>   * *AOR:* Adjusted odds ratio (each independent variable)
>   * *lower_CI:* Lower confidence interval (each independent variable)
>   * *upper_CI:* Upper confidence interval (each independent variable)
>   * *variable:* Independent variable
> 
> Here is the script I am using in *R*:
> 
> *# Calculate the standard error (seTE)*
> *
> *
> data$seTE <- (log(data$upper_CI) - log(data$lower_CI)) / (2 * 1.96)
> 
> *# Meta-analysis*
> *
> *
> meta_analysis <- metagen(TE = log(data$AOR),
> seTE = data$seTE,
> data = data,
> studlab = data$study_id,
> comb.fixed = TRUE,
> comb.random = TRUE)
> 
> *I would like to know if this script is correct for achieving my goals of:*
> 
>   * Calculating the pooled AOR and the 95% confidence interval.
>   *
>     Calculating the I² and the p-value to assess heterogeneity.
> 
> Look at the dataset:
> 
> Any feedback or suggestions for improvement would be greatly appreciated!
> 
> Thank you!
> 
> *Sancho Xavier*
> Candidate for Postgraduate Programme in Epidemiology in Public Health
> MBA in Data Science and Analytics at USP (ongoing)
> *Linkedin:* linkedin.com/in/sancho-xavier-59565a18a
> *Orcid iD:* https://orcid.org/0000-0001-9493-4098
> *Web of Science (Clarivate):* 
> https://www.webofscience.com/wos/author/record/GON-5675-2022 
> <https://www.webofscience.com/wos/author/record/GON-5675-2022>
> *Reference Citation Analysis (RCA): 
> *https://referencecitationanalysis.com/00001471 
> <https://referencecitationanalysis.com/00001471>
> *Whatsapp: *+258 852255846
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-- 
Michael



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