[R-meta] meta-analysis with 2 within-subject variables

[zeffiro neurometrika.org]

 I have a question about how to set up the metafor code to perform a meta- analysis using an experimental design that is fairly common in cross-over treatment studies.

 We have continuous outcome measures (mean and sd) from studies in which each participant was measured 4 times: 1) in both drug and placebo conditions and 2) both before and after exposure - in a cross-over design. So,
each study is a 2x2 factorial design with 2 repeated measures.

Although it looks to me as if rma.mv is the appropriate program for this analysis, I am having difficulty determining the syntax showing how to set things up to properly handle the within subject correlation and was hoping that someone could point me to a worked example to use as a guide. I have not found anything
addressing meta-analysis modeling of multiple repeated measures in a single group.

We are starting out with only 5 studies in the initial meta-analysis.

Thanks in advance for any guidance you can provide.

Regards,
Tom


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