[R-meta] Fwd: Question on Umbrella review and other types

[Dr. Gerta Rücker]

Hi Imran,

I think the publication of new studies justifies an updated review, particularly if the existing reviews have inconsistent or inconclusive results.

You should, however, avoid to be selective with the studies, let alone selective based on the results! This would be publication bias. What you can do if you suppose there is a time effect is a metaregression with "year published" as a covariate.

Best,
Gerta


UNIVERSITÄTSKLINIKUM FREIBURG
Institute for Medical Biometry and Statistics

Dr. Gerta Rücker
Guest Scientist

Stefan-Meier-Straße 26 · 79104 Freiburg
gerta.ruecker using uniklinik-freiburg.de

https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker


-----Ursprüngliche Nachricht-----
Von: Im via R-sig-meta-analysis <r-sig-meta-analysis using r-project.org> 
Gesendet: Montag, 22. April 2024 20:46
An: R Special Interest Group for Meta-Analysis <r-sig-meta-analysis using r-project.org>
Cc: Im <aligners79 using gmail.com>
Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types

Dear All!
Many thanks indeed for your much valuable replies.

My research is based on "Prognosis in relation to age in a carcinoma".
The study results are "young age patients have better prognosis", "old age
have worst prognosis", "age has not affect on prognostication" etc....
Is it possible to be selective in the studies in terms of time of studies
published etc., so that there can be some change in the analysis
than previous ones ?

With such a trivial number (only two) of previous SRMA, it seems better to
conduct a new SRMA instead. But I am bit concerned whether it is Ok
to conduct a new SRMA when the previously SRMA have been published with a
gap of just couple of years (2020 and 2021)?

So, if there is no problem in conducting a new SRMA, then I would be add
the studies and proceed with the routine "meta" package in R studios for
forest plots and funnel plots ?

best regards,
Imran

On Mon, Apr 22, 2024 at 6:35 PM Dr. Gerta Rücker via R-sig-meta-analysis <
r-sig-meta-analysis using r-project.org> wrote:

> Yes,I have noted that the word "umbrella" has experienced a change of
> meaning over the last years. In former times (that is, before network
> meta-analysis became popular) it meant to conduct a number of pairwise
> meta-analyses for different treatments for the same condition in the same
> review. Since this is now better done using network meta-analysis, they now
> use the term for something different, namely overview of overviews, and
> this is what the original poster meant.
>
> As I understand, in the described situation, a re-analysis is planned,
> thus I am not sure whether a special R package is needed.
>
> Best,
> Gerta
>
> UNIVERSITÄTSKLINIKUM FREIBURG
> Institute for Medical Biometry and Statistics
>
> Dr. Gerta Rücker
> Guest Scientist
>
> Stefan-Meier-Straße 26 · 79104 Freiburg
> gerta.ruecker using uniklinik-freiburg.de
>
> https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker
>
>
> -----Ursprüngliche Nachricht-----
> Von: Michael Dewey <lists using dewey.myzen.co.uk>
> Gesendet: Montag, 22. April 2024 17:23
> An: R Special Interest Group for Meta-Analysis <
> r-sig-meta-analysis using r-project.org>
> Cc: Dr. Gerta Rücker <gerta.ruecker using uniklinik-freiburg.de>
> Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types
>
> There is a package https://cran.r-project.org/package=metaumbrella on
> CRAN which performs umbrella reviews. Whether what they mean by umbrella
> is what you mean is open to question.
>
> Michael
>
> On 22/04/2024 15:44, Dr. Gerta Rücker via R-sig-meta-analysis wrote:
> > Hi (whoever you are),
> >
> > If you want to repeat the old meta-analysis anyway, assuming that all
> studies adhere to some common well-defined inclusion criteria,  then why
> not conducting a meta-analysis including the union of all studies included
> in the two older reviews and the new studies? This would simply be an
> updated review, not necessarily an umbrella review.
> >
> > Best,
> > Gerta
> >
> >
> > UNIVERSITÄTSKLINIKUM FREIBURG
> > Institute for Medical Biometry and Statistics
> >
> > Dr. Gerta Rücker
> > Guest Scientist
> >
> > Stefan-Meier-Straße 26 · 79104 Freiburg
> > gerta.ruecker using uniklinik-freiburg.de
> >
> >
> https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker
> >
> > -----Ursprüngliche Nachricht-----
> > Von: Im via R-sig-meta-analysis <r-sig-meta-analysis using r-project.org>
> > Gesendet: Montag, 22. April 2024 15:47
> > An: r-sig-meta-analysis using r-project.org
> > Cc: Im <aligners79 using gmail.com>
> > Betreff: [R-meta] Fwd: Question on Umbrella review and other types
> >
> > ---------- Forwarded message ---------
> > From: Im <aligners79 using gmail.com>
> > Date: Mon, Apr 22, 2024 at 12:56 PM
> > Subject: Question on Umbrella review and other types
> > To: <r-sig-meta-analysis using r-project.org>
> >
> >
> >
> > Hello!
> >   I am planning to do an Umbrella review.
> >
> > The number of systematic/meta analysis are two. Rest of the studies are
> 3-4
> > new studies published after or almost at same time of these two reviews.
> >
> > My question is can I conduct the Umbrella review ? If not then is there
> any
> > other type of review that could be performed ?  I want to include the
> > previous systematic/meta reviews. I also plan to repeat already performed
> > meta-analysis. Can I add the meta analysis studies HRs and new studies to
> > make another meta-analysis ?
> >
> > Please guide me which review could be the best in this situation.
> > best regards
> >
> >       [[alternative HTML version deleted]]
> >
> > _______________________________________________
> > R-sig-meta-analysis mailing list @ R-sig-meta-analysis using r-project.org
> > To manage your subscription to this mailing list, go to:
> > https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
> > _______________________________________________
> > R-sig-meta-analysis mailing list @ R-sig-meta-analysis using r-project.org
> > To manage your subscription to this mailing list, go to:
> > https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
> >
> >
>
> --
> Michael
> _______________________________________________
> R-sig-meta-analysis mailing list @ R-sig-meta-analysis using r-project.org
> To manage your subscription to this mailing list, go to:
> https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
>

	[[alternative HTML version deleted]]

_______________________________________________
R-sig-meta-analysis mailing list @ R-sig-meta-analysis using r-project.org
To manage your subscription to this mailing list, go to:
https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis