[R-meta] contour enhanced funnel plots when using function of sample size

Tori Peña Tor|@Pen@ @end|ng |rom @tonybrook@edu
Wed May 25 21:40:47 CEST 2022


Hi folks,

I wanted to follow-up this question and ask if there is a way (or is it
recommended) to generate a color-enhanced funnel plot on a rma.mv object?
Thanks in advance!

On Tue, May 24, 2022 at 6:00 AM Guido Schwarzer <sc using imbi.uni-freiburg.de>
wrote:

> Am 24.05.22 um 10:46 schrieb Brendan Hutchinson:
>
> > [...]
> > My question is specifically whether there is a means of generating a
> contour enhanced funnel plot with pseudo confidence regions when using a
> function of sample size on the y axis. According to the R documentation,
> this isn't possible. I wanted to ask if anyone knew of any means to achieve
> this or perhaps a workaround (unless this is some inherent issue to the use
> of a function of sample size that I'm not seeing).
>
> The sample size does not contain any information on the statistical
> significance of a study result. For example, for a binary outcome:
>
>  > meta::metabin(1, 100, 2, 100)$pval
> [1] 0.5688381
>  > meta::metabin(25, 100, 50, 100)$pval
> [1] 0.0005287824
>
> Both studies have a total sample size of 200, however, depending on the
> number of events, the studies have very different p-values.
>
> The same argument can be made for a continuous outcome, studies with the
> same sample sizes and mean values can have very different standard
> deviations leading to different p-values.
>
> Best,
>
> Guido
>
> --
> Dr. Guido Schwarzer
> Institute of Medical Biometry and Statistics,
> Faculty of Medicine and Medical Center - University of Freiburg
>
> Postal address: Zinkmattenstr. 6a, D-79108 Freiburg
>
> Mail: sc using imbi.uni-freiburg.de
> Homepage: https://www.imbi.uni-freiburg.de/
>
> ORCID iD: https://orcid.org/0000-0001-6214-9087
> R-book: https://www.springer.com/gp/book/9783319214153
>
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-- 
*Tori Peña <https://www.linkedin.com/in/toripena/> *(she/her/ella)
Doctoral Candidate, Cognitive Psychology
Dept. of Psychology
Stony Brook University
Stony Brook, NY 11790-2500
[image: Stony Brook University logo]

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