[R-meta] Predictive interval in MA with less than 10 studies

Philippe Tadger ph|||ppet@dger @end|ng |rom gm@||@com
Mon Sep 27 10:34:26 CEST 2021


Dear R-sig-MA community

According to Cochrane manual: it's recommended to not trust in the PI 
when there are fewer than 10 studies because such calculation relies on 
the assumption of normality. Is there a way to check formally on each 
case when using less than 10 studies is not safe for PI calculation?. I 
can understand this limitation when the PI is calculated through a 
method that uses the methods of moments (or exact calculations like 
Riley 2001), but when the PI comes from a model that uses ML/REML (or 
iterative methods with identifiable likelihood) or Bayesian, such 
concern cannot exist. I would like to find confirmation or refutation of 
this idea.


In advance,  your time and shared wisdom are appreciated.
-- 
Kind regards/Saludos cordiales
*Philippe Tadger*
ORCID <https://orcid.org/0000-0002-1453-4105>, Reseach Gate 
<https://www.researchgate.net/profile/Philippe-Tadger>


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