[R-meta] meta-analysis of mean differences with only the difference and its SD

[Guido Schwarzer]

Am 05.10.21 um 16:00 schrieb Martin Lobo:

> Hi Gerta, I'm sorry, I was later.
>
> I need to do a mean difference analysis. For example, there was a decrease in LDL with a drug versus a placebo. But I do not have the average value of each branch with its standard deviations. I have the difference of each branch with its confidence intervals. [...]

You can use metagen() from R package meta if you have mean differences 
and CI limits. Note, you should know how the original confidence 
intervals were calculated, i.e. based on normal approximation or 
t-distribution, and provide the corresponding information (see attached 
R code).

Best, Guido

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