[R-meta] Meta-Analisys whit events numbers, RR, OR and HR. It's possibe?

Michael Dewey ||@t@ @end|ng |rom dewey@myzen@co@uk
Sun Jan 24 13:12:17 CET 2021


Dear Martin

As Gerta says HR is different but if you want to try to retrieve the raw 
frequencies from OR and RR there is a package on CRAN which claims to do 
that

https://cran.r-project.org/package=estimraw

There is a reference to a supporting article as well you you can check 
what they are doing.

Michael

On 23/01/2021 18:14, Martin Lobo wrote:
> Hi Gerta !!!
> yes gerta, it's like you said.
> I have seen that with metagen it could be done but I think it would open to pass everything to RR, OR or HR to use the Ln of these, and with the p, or IC95% I could get the standard errors.
> But I don't quite understand what it would be like.
> Thanks
> 
> 
> 
> 
> 
> 
> 
> Lorenzo Martín Lobo MTSAC, FACC, FESC
> Especialista Jerarquizado en Cardiología
> Jefe de Dpto Enf. Cardiovasculares y Cardiometabolismo Hospital Militar Campo de Mayo.
> Jefe de Cardiología Hospital Militar Campo de Mayo
> Ex Jefe de Unidad Coronaria Hospital Militar Campo de Mayo
> Miembro Titular de la Sociedad Argentina de Cardiología
> Fellow American College of Cardiology
> Fellow European Society of Cardiology
> Ex Miembro del Area de Investigación de la SAC
> Ex Director del Consejo de Aterosclerosis y Trombosis de la SAC
> Miembro Asesor del Consejo de Aterosclerosis y Trombosis de la SAC
> Ex Director del Consejo de Epidemiología y Prevención Cardiovascular de la SAC
> 
> Miembro Asesor del Consejo de Epidemiología y Prevención Cardiovascular de la SAC
> 
> 
> Experto en Lipidos de la Sociedad Argentina de Lipidos.
> Miembro de la Sociedad Argentina de Lipidos.
> Instructor de ACLS de la American Heart Association
> 
> 
> ________________________________
> De: Dr. Gerta Rücker <ruecker using imbi.uni-freiburg.de>
> Enviado: sábado, 23 de enero de 2021 15:09
> Para: Martin Lobo <mlobo4370 using hotmail.com>; r-sig-meta-analysis using r-project.org <r-sig-meta-analysis using r-project.org>
> Asunto: Re: [R-meta] Meta-Analisys whit events numbers, RR, OR and HR. It's possibe?
> 
> 
> Dear Martin,
> 
> My first question is: What kind of outcome do you have? HR is for a time-to-event outcome, for example survival, the others are for a binary outcome, for example death within a certain (fixed) time interval. They don't describe the same thing.
> 
> For extracting data for a time-to-event outcome, there are a number of papers, for example
> 
> Tierney et al. (providing an excel sheet): https://trialsjournal.biomedcentral.com/articles/10.1186/1745-6215-8-16<https://na01.safelinks.protection.outlook.com/?url=https%3A%2F%2Ftrialsjournal.biomedcentral.com%2Farticles%2F10.1186%2F1745-6215-8-16&data=04%7C01%7C%7Cd4e0812098a143f04ac608d8bfc9f345%7C84df9e7fe9f640afb435aaaaaaaaaaaa%7C1%7C0%7C637470221384519523%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=XEb%2FKUDgweUfvQmEgIYoL%2BmZhOY7d8yS%2FtL3w9HSfOg%3D&reserved=0>
> 
> Parmar et al.: https://doi.org/10.1002/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0.CO;2-8<https://na01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1002%2F(SICI)1097-0258(19981230)17%3A24%253C2815%3A%3AAID-SIM110%253E3.0.CO%3B2-8&data=04%7C01%7C%7Cd4e0812098a143f04ac608d8bfc9f345%7C84df9e7fe9f640afb435aaaaaaaaaaaa%7C1%7C0%7C637470221384529519%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=pm5gaiTo5k6etxSAXGyDdHej3DZNvyhSm03saP7hu9o%3D&reserved=0>
> 
> Best,
> Gerta
> 
> Am 23.01.2021 um 13:23 schrieb Martin Lobo:
> 
> Hi everyone !!!
> I need performed a meta-analisys, but i have a problem whith de data extractions.
> In 3 papers I have:
> event.e, n.e, event.c, n.c (or  ai=tpos, bi=tneg, ci=cpos, di=cneg)
> 
> In another papers I have:
> 
> n.e, n.c and HR
> In another papers I have:
> 
> n.e, n.c and OR
> In another papers I have:
> 
> n.e, n.c and RR
> 
> I have read in the cochraine manual that it could be meta-analyzed, but I don't know how.
> 
> Should I transform everything to the same summary measure?
> 
> How would these measures be transformed?
> 
> How would the meta-analysis with the transformed measurements.
> 
> Sorry so many questions but I need your help.
> 
> Regards
> 
> 
> 
> 
> 
> 
> Lorenzo Mart�n Lobo MTSAC, FACC, FESC
> Especialista Jerarquizado en Cardiolog�a
> Jefe de Dpto Enf. Cardiovasculares y Cardiometabolismo Hospital Militar Campo de Mayo.
> Jefe de Cardiolog�a Hospital Militar Campo de Mayo
> Ex Jefe de Unidad Coronaria Hospital Militar Campo de Mayo
> Miembro Titular de la Sociedad Argentina de Cardiolog�a
> Fellow American College of Cardiology
> Fellow European Society of Cardiology
> Ex Miembro del Area de Investigaci�n de la SAC
> Ex Director del Consejo de Aterosclerosis y Trombosis de la SAC
> Miembro Asesor del Consejo de Aterosclerosis y Trombosis de la SAC
> Ex Director del Consejo de Epidemiolog�a y Prevenci�n Cardiovascular de la SAC
> 
> Miembro Asesor del Consejo de Epidemiolog�a y Prevenci�n Cardiovascular de la SAC
> 
> 
> Experto en Lipidos de la Sociedad Argentina de Lipidos.
> Miembro de la Sociedad Argentina de Lipidos.
> Instructor de ACLS de la American Heart Association
> 
> 
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> 
> 
> 
> 
> 
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-- 
Michael
http://www.dewey.myzen.co.uk/home.html



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