[R-meta] Meta-Analisys whit events numbers, RR, OR and HR. It's possibe?

[Martin Lobo]

Hi Gerta !!!
yes gerta, it's like you said.
I have seen that with metagen it could be done but I think it would open to pass everything to RR, OR or HR to use the Ln of these, and with the p, or IC95% I could get the standard errors.
But I don't quite understand what it would be like.
Thanks







Lorenzo Martín Lobo MTSAC, FACC, FESC
Especialista Jerarquizado en Cardiología
Jefe de Dpto Enf. Cardiovasculares y Cardiometabolismo Hospital Militar Campo de Mayo.
Jefe de Cardiología Hospital Militar Campo de Mayo
Ex Jefe de Unidad Coronaria Hospital Militar Campo de Mayo
Miembro Titular de la Sociedad Argentina de Cardiología
Fellow American College of Cardiology
Fellow European Society of Cardiology
Ex Miembro del Area de Investigación de la SAC
Ex Director del Consejo de Aterosclerosis y Trombosis de la SAC
Miembro Asesor del Consejo de Aterosclerosis y Trombosis de la SAC
Ex Director del Consejo de Epidemiología y Prevención Cardiovascular de la SAC

Miembro Asesor del Consejo de Epidemiología y Prevención Cardiovascular de la SAC


Experto en Lipidos de la Sociedad Argentina de Lipidos.
Miembro de la Sociedad Argentina de Lipidos.
Instructor de ACLS de la American Heart Association


________________________________
De: Dr. Gerta Rücker <ruecker using imbi.uni-freiburg.de>
Enviado: sábado, 23 de enero de 2021 15:09
Para: Martin Lobo <mlobo4370 using hotmail.com>; r-sig-meta-analysis using r-project.org <r-sig-meta-analysis using r-project.org>
Asunto: Re: [R-meta] Meta-Analisys whit events numbers, RR, OR and HR. It's possibe?


Dear Martin,

My first question is: What kind of outcome do you have? HR is for a time-to-event outcome, for example survival, the others are for a binary outcome, for example death within a certain (fixed) time interval. They don't describe the same thing.

For extracting data for a time-to-event outcome, there are a number of papers, for example

Tierney et al. (providing an excel sheet): https://trialsjournal.biomedcentral.com/articles/10.1186/1745-6215-8-16<https://na01.safelinks.protection.outlook.com/?url=https%3A%2F%2Ftrialsjournal.biomedcentral.com%2Farticles%2F10.1186%2F1745-6215-8-16&data=04%7C01%7C%7Cd4e0812098a143f04ac608d8bfc9f345%7C84df9e7fe9f640afb435aaaaaaaaaaaa%7C1%7C0%7C637470221384519523%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=XEb%2FKUDgweUfvQmEgIYoL%2BmZhOY7d8yS%2FtL3w9HSfOg%3D&reserved=0>

Parmar et al.: https://doi.org/10.1002/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0.CO;2-8<https://na01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1002%2F(SICI)1097-0258(19981230)17%3A24%253C2815%3A%3AAID-SIM110%253E3.0.CO%3B2-8&data=04%7C01%7C%7Cd4e0812098a143f04ac608d8bfc9f345%7C84df9e7fe9f640afb435aaaaaaaaaaaa%7C1%7C0%7C637470221384529519%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=pm5gaiTo5k6etxSAXGyDdHej3DZNvyhSm03saP7hu9o%3D&reserved=0>

Best,
Gerta

Am 23.01.2021 um 13:23 schrieb Martin Lobo:

Hi everyone !!!
I need performed a meta-analisys, but i have a problem whith de data extractions.
In 3 papers I have:
event.e, n.e, event.c, n.c (or  ai=tpos, bi=tneg, ci=cpos, di=cneg)

In another papers I have:

n.e, n.c and HR
In another papers I have:

n.e, n.c and OR
In another papers I have:

n.e, n.c and RR

I have read in the cochraine manual that it could be meta-analyzed, but I don't know how.

Should I transform everything to the same summary measure?

How would these measures be transformed?

How would the meta-analysis with the transformed measurements.

Sorry so many questions but I need your help.

Regards






Lorenzo Mart�n Lobo MTSAC, FACC, FESC
Especialista Jerarquizado en Cardiolog�a
Jefe de Dpto Enf. Cardiovasculares y Cardiometabolismo Hospital Militar Campo de Mayo.
Jefe de Cardiolog�a Hospital Militar Campo de Mayo
Ex Jefe de Unidad Coronaria Hospital Militar Campo de Mayo
Miembro Titular de la Sociedad Argentina de Cardiolog�a
Fellow American College of Cardiology
Fellow European Society of Cardiology
Ex Miembro del Area de Investigaci�n de la SAC
Ex Director del Consejo de Aterosclerosis y Trombosis de la SAC
Miembro Asesor del Consejo de Aterosclerosis y Trombosis de la SAC
Ex Director del Consejo de Epidemiolog�a y Prevenci�n Cardiovascular de la SAC

Miembro Asesor del Consejo de Epidemiolog�a y Prevenci�n Cardiovascular de la SAC


Experto en Lipidos de la Sociedad Argentina de Lipidos.
Miembro de la Sociedad Argentina de Lipidos.
Instructor de ACLS de la American Heart Association


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