[R-meta] converting escalc ROM outputs to the log-2 scale

Divya Ravichandar d|vy@ @end|ng |rom @econdgenome@com
Fri Dec 11 23:36:04 CET 2020


Hi all

I have a question around changing the scale of *yi *and *vi *exported
from *escalc()
*function when using *measure=ROM.* Based on the documentation, this
function exports *yi *in natural log (ln) scale. --> yi =
ln(grp1-mean/grp2-mean) and then the associated vi.

I am interested in obtaining the *log-2 fold change. *Is there a way to
convert yi & vi from *escalc(measure = ROM,...) *to this scale. Would it be
reasonable to simply transform the values by converting from log-e -> log-2
scale by
yi_new = yi/log(2) and vi_new = vi/log(2)

Thank you

-- 
*Divya Ravichandar*
Scientist
Second Genome

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