[R-meta] Meta-analysis with only p.values and N?

Raquel Cumeras Olmeda r@que|@cumer@@ @end|ng |rom urv@c@t
Wed Dec 9 23:30:06 CET 2020


Thanks for your inputs, after checking all the possibilities, I am afraid that we cannot do the forest plot because we don't have all the needed input data.
Raquel

-----Original Message-----
From: Michael Dewey <lists using dewey.myzen.co.uk> 
Sent: Saturday, December 5, 2020 8:16 AM
To: t.saueressig using gmx.de
Cc: Raquel Cumeras Olmeda <raquel.cumeras using urv.cat>; r-sig-meta-analysis using r-project.org
Subject: Re: [R-meta] Meta-analysis with only p.values and N?

Those methods have their uses but if Raquel wants a forest plot I do not think they generate the required effect size with its confidence interval.

Michael

On 05/12/2020 14:19, t.saueressig using gmx.de wrote:
> Dear Raquel,
> 
> in Boerenstein et al. 2009 (Handbook) there is a description of a 
> method to combine p values for a pooled p value. Maybe that would be a solution?
> 
> Regards,
> 
> Tobias Saueressig
> 
> Am 05.12.2020 12:21 schrieb Michael Dewey <lists using dewey.myzen.co.uk>:
> 
>     Dear Raquel
> 
>     If you have the means or the difference in means as well then you can
>     back-calculate what you need but if not I am afraid I can see no way
>     forward although other smarter list readers may be able to help.
> 
>     Michael
> 
>     On 04/12/2020 18:45, Raquel Cumeras Olmeda wrote:
>      > Dear all,
>      >
>      > We are trying to do a meta-analysis of metabolomics data.
>      > In metabolomics, we study the changes of the concentrations of
>     compounds in biofluids.
>      >
>      > So, for the data I am trying to analyze I have the p.value of the
>     relevant compounds and the N of the patients and controls.
>      >
>      > We tried to do a forest plot, but we don't know how to do it with
>     only the p.value and the N.
>      >
>      > Any help would be more than welcome!
>      >
>      > Raquel Cumeras
>      >
>      >
>     
> ----------------------------------------------------------------------
> -------------------------
> 
>      > Raquel Cumeras, Ph.D.
>      > Marie Curie Postdoctoral Research Fellow
>      > - Institut d'Investigaci  Sanit ria Pere Virgili (IISPV, ES).
>     Metabolomics Platform<http://metabolomicsplatform.com/>.
>      > - University of California Davis (UC Davis, USA). Fiehn lab.
>      > - Affiliated to Universitat Rovira i Virgili (URV, ES) and
>     CIBERDEM (ISCIII, ES).
>      >
>      > website: https://raquelcumeras.wordpress.com/
>      > e_mail: raquel.cumeras using iispv.cat<mailto:raquel.cumeras using iispv.cat>
>     // rcumeras using ucdavis.edu<mailto:rcumeras using ucdavis.edu> //
>     raquel.cumeras using urv.cat<mailto:raquel.cumeras using urv.cat>
>      > ORCiD: 0000-0003-4663-4247
>      > Pronouns: she/her
>      >
>     
> ----------------------------------------------------------------------
> -------------------------
> 
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>      >
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>     -- 
>     Michael
>     http://www.dewey.myzen.co.uk/home.html
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