[R-meta] Sample size and continuity correction

[James Meyer]

Dear Gerta,

In relation to the Cis overlapping. I have a diagnostic test accuracy meta-analysis with the primary studies using small sample sizes. Therefore the confidence intervals for sensitivity and specificity are wide and all 10 studies overlap.   This within study variability seems to mask any between study heterogeneity.  Is it possible that a lack of precision in primary studies can make it look like the meta-analysis has low heterogeneity?

James Meyer DVM MSc

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