[R-meta] convergence in Mada

Philipp Doebler doeb|er @end|ng |rom @t@t|@t|k@tu-dortmund@de
Wed Jun 19 14:59:09 CEST 2019

Hi James,

I have rarely had convergence problems. There are three potential problems:

(1) Low number of studies (5 model parameters...) but mada throws a warning
if I remember correctly.
(2) Little variance in the false positive rates and/or sensitivities.
Especially relevant if all studies have the same sensitivity of, say, 95%.
This can sometimes lead to a degenerate covariance matrix of the bivarate
random effect.
(3) A perfect between study correlation of logit(sens) and logit(fpr). If
there is any suspicion, calculate the correlation matrix with cov2cor.

Also have a look at all standard errors and confidence intervals. The
recent simulation study of Vogelsang et al. (2018) discusses convergence
issues of mada (and other packages).

Kind wishes,

On Wed, Jun 19, 2019 at 2:32 PM James Meyer <
outlook_655291802F3BAFF3 using outlook.com> wrote:

> How can you tell if convergence has been accomplished using the reitsma()
> function in mada ? Which package do you recommend using for DTA
> meta-analysis if you have a small number of studies?
> Sincerely
> James C Meyer
> Sent from Mail<https://go.microsoft.com/fwlink/?LinkId=550986> for
> Windows 10
>         [[alternative HTML version deleted]]
> _______________________________________________
> R-sig-meta-analysis mailing list
> R-sig-meta-analysis using r-project.org
> https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis

Prof. Dr. Philipp Doebler
Technische Universität Dortmund
Fakultät Statistik
Vogelpothsweg 87
44227 Dortmund

Tel.: +49 231-755 8259
Fax: +49 231-755 3918
doebler using statistik.tu-dortmund.de

Wichtiger Hinweis: Die Information in dieser E-Mail ist vertraulich. Sie
ist ausschließlich für den Adressaten bestimmt. Sollten Sie nicht der
für diese E-Mail bestimmte Adressat sein, unterrichten Sie bitte den
Absender und vernichten Sie diese Mail. Vielen Dank.
Unbeschadet der Korrespondenz per E-Mail, sind unsere Erklärungen
ausschließlich final rechtsverbindlich, wenn sie in herkömmlicher
Schriftform (mit eigenhändiger Unterschrift) oder durch Übermittlung
eines solchen Schriftstücks per Telefax erfolgen.

Important note: The information included in this e-mail is confidential.
It is solely intended for the recipient. If you are not the intended
recipient of this e-mail please contact the sender and delete this
message. Thank you.
Without prejudice of e-mail correspondence, our statements are only
legally binding when they are made in the conventional written form
(with personal signature) or when such documents are sent by fax.

	[[alternative HTML version deleted]]

More information about the R-sig-meta-analysis mailing list