[R-meta] meta-analytic models with overdispersed data

Dave Daversa ddaversa at gmail.com
Thu Jul 27 13:06:45 CEST 2017

Hi all:

I have read numerous websites and searched online forums for help with the
following meta-analysis question but still am not clear what the answer

My study is concerned with the magnitudes of effects (using hedges d as a
measure of effect size).  So, I have taken the absolute value of the effect
size to use as my response variables in random effects models (rma
function).  However, t*he "absolute" effect sizes are not normally
distributed (rather a negative binomial distribution).  I presume that the
model run via rma() is not appropriate*, given assumptions of normality of
the data?

I have read discouraging remarks about log-transforming effect sizes for

I understand that bootstrapping can be done to estimate confidence
intervals for the data, but what model to use to estimate mean effect sizes
is still unclear to me.

If you can provide any answers and/or point me to references to clarify how
I model overdispersed data for meta-analysis, it would be a great help.

Many thanks for your time and assistance.

*David Daversa, PhD*

*Postdoctoral Researcher*

*Institute for Integrative Biology, University of
Liverpoolddaversa at gmail.com <ddaversa at gmail.com>ddaversa at liv.ac.uk
<ddaversa at wustl.edu>*

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