[R-sig-Epi] help
董忠信
06dongsheng at 163.com
Wed Sep 4 15:10:04 CEST 2013
hi, dear friend , i am dealing with a survival data for cancer. a variable progression doesn't satisfy PH assumption, i have tried the paramatric survival models, but they did not fit very well. at last ,i tried the extension of Cox model with time-dependent variable, finding that the model fit well with the smallest AIC, and the average or weight HR is 1.6. when progression occured in the first follow-up year, the HR was biggest ,and HR gone down in the second year, like the picture showed. after having reading over the examples in R help documents, i am not sure if i can plot nomogram for 5 year survival prediction. and cph may did not work well when applied to the Cox model with time-dependent variable, i can use coxph, set " tt=function(x,t,...) {x *log(t)}" as a alternative. but most important, how can i complete the nomogram ,validate and calibrate.ie.setup may help,but not show in detail.
can you help me to plot a nomogram? thanks for reading.
Dong
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