[R-sig-eco] FW: mixed effect model: compare seed families
Liza Comita
lsc2125 at columbia.edu
Thu Jan 21 16:32:23 CET 2010
Re: FW: mixed effect model: compare seed families
To get around the problem of 'lmer()' not returning p values, Bates
recommends using a Markov Chain Monte Carlo sample to evaluate the
properties of individual coefficients. This is much easier than it
may sound!
If you download and install the library 'languageR', there is a
function called
'pvals.fnc()', which computes p-values and MCMC confidence intervals
for mixed models. It is very simple to use.
'pvalues.fnc' internally calls the functions 'mcmcsamp()' and
'HPDinterval()', which are what Bates recommends, to generate 95% MCMC
confidence intervals and p values. It also supplies p values based on
the t statistic (using the number of observations minus the number of
fixed-effects coefficients as degrees of freedom), but warns that this
p-value is anti-conservative. So, the MCMC intervals and p values are
probably the best to use.
However, and this may be a problem for your particular design, the
'pvalues.fnc' help file warns: "Currently, MCMC sampling for
generalized linear mixed models may not work off the shelf when there
is more than one random intercept in the model." But these functions
are constantly being updated, so hopefully by now it can handle more
than 1 random effect.
Also, for information about why lmer does not supply p-values, see
these sites:
https://stat.ethz.ch/pipermail/r-help/2006-May/094765.html
http://tolstoy.newcastle.edu.au/R/help/06/08/32409.html
Hope that helps!
Liza Comita
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