The new package obsSens is now on the CRAN mirrors.  This package has tools for doing senstitivity analysis for observational studies.
 
The common criticism of observational studies is that there is the possibility of an unmeasured variable that is related to both the response and the predictor of interst that could explain the observed relationship.  The sensitivity analysis is a "What If?" game where you specify potential relationships between the unmeasured variable and the response and predictor variable and see how that affects the relationship between predictor and response.
 
 

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