Hi all,

I have just uploaded the hbim package. This package does calculations related to the Hill/Bliss independence model as applied to mulitcomponent vaccines. Specifically, the package caculates expected relative risk and proportion protected assuming normally distributed log10 transformed antibody dose for a several component vaccine. It uses Hill models for each component which are combined under Bliss independence.

A description of the motivation for the package is published in:

Saul A, Fay MP (2007). Human Immunity and the Design of Multi-Component, Single Target Vaccines. PLoS ONE 2(9): e850. doi:10.1371/jounal.pone.0000850 (Available at http://www.plosone.org/)

Please let me know if you have any comments about or corrections for the package. 
 
Thanks, 

Mike
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Michael P. Fay, PhD
Mathematical Statistician
National Institute of Allergy and Infectious Diseases
Tel: 301-451-5124               Fax:301-480-0912
(U.S. postal mail address)                           
6700B Rockledge Drive MSC 7609
Bethesda, MD 20892-7609
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Bethesda, MD 20817
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