[R-pkgs] DNAmixturesLite and KinMixLite

Peter Green m@pjg @end|ng |rom br|@to|@@c@uk
Wed Apr 12 10:18:21 CEST 2023


Dear all,

We are pleased to announce that CRAN now hosts our packages 
DNAmixturesLite and KinMixLite.

These are fully R-based versions of our packages DNAmixtures and KinMix, 
which rely on a commercial software, HUGIN, for performing efficient 
computations in Bayesian networks. The lite versions rely instead on 
gRain for such computations.

DNAmixtures provides statistical methods for DNA mixture analysis and 
has been used to provide statistical evidence pertaining to DNA in 
several criminal cases in the UK and Denmark. The purpose of the newly 
released lite version is to allow users without a HUGIN software license 
to experiment with the statistical methodology. While the lite version 
aims to provide full functionality, it is noticeably less efficient than 
the original DNAmixtures package. For details on implementation and 
methodology see <https://dnamixtures.r-forge.r-project.org/>.

KinMix builds upon DNAmixtures and is a toolbox of methods for inference 
about relationships between contributors to a DNA mixture and other 
individuals of known genotype: a basic example would be testing whether 
a contributor to a mixture is the father of a child of known genotype. 
KinMixLite builds upon DNAmixturesLite and provides most of the 
functionality of the KinMix package, but with some loss of efficiency. 
The package implements the methods introduced in Green, P. J. and 
Mortera, J. (2017) <doi:10.1016/j.fsigen.2017.02.001> and Green, P. J. 
and Mortera, J. (2021) <doi:10.1111/rssc.12498>.

Regards,
Therese Graversen and Peter Green



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