[R-pkgs] LW1949 – new package for evaluating dose-effect experiments

Adams, Jean jvadams at usgs.gov
Fri Dec 4 22:18:50 CET 2015

LW1949 1.0.0 is now available on CRAN.

LW1949 automates the steps taken in Litchfield and Wilcoxon’s (1949) manual
approach to evaluating dose-effect experiments. Letting the computer do the
work saves time and yields the best fit possible using the Litchfield
Wilcoxon approach (by minimizing the chi-squared statistic).

A brief demonstration of LW1949 is given in this web app,


An example of how to use the functions in LW1949 is given in this vignette,


Litchfield, JT Jr. and F Wilcoxon. 1949. A simplified method of evaluating
dose-effect experiments. Journal of Pharmacology and Experimental
Therapeutics 96(2):99-113.



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Jean V. Adams​​
U.S. Geological​​ Survey ​​
Great Lakes Science Center
223 East Steinfest Road ​​
Antigo, WI 54409  USA ​​

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