Hi All,

Since R is used primarily as a statistical package by individuals using
statistics to answer questions it makes sense to ask a question such as
this.  Oftentimes individuals have encountered similar issues as the poster
and can quickly point them in the correct direction - that is all I am
asking.

Quite honestly I have been on the R list for several years and have seen
*plenty* of people asking for statistical advice.  Now of course often
times the individual is flamed (something that the R list is notorious for)
so Bert, I personally thank you for being at least courteous to offer
advice.

Perhaps someone on the list may have a more constructive comment.


On Wed, Aug 28, 2013 at 9:25 AM, Bert Gunter <gunter.berton@gene.com> wrote:

> This is not an R question. Post elsewhere. Better yet, contact a local
> statistical consultant.
>
> -- Bert
>
> On Wed, Aug 28, 2013 at 7:18 AM, Donald Catanzaro <dgcatanzaro@gmail.com>
> wrote:
> > Good Day All,
> >
> > I am working with a diagnostic test and comparing the new test to an old
> > test.  Normally I would be able to calculate sensitivity and specificity
> > quite easily.
> >
> > However, the 'gold standard' that I am comparing my new diagnostic with
> is
> > really 'gold-plated' in that sometimes the 'gold standard' fails
> completely
> > and I have no data from the 'gold standard' but I might have data from
> the
> > diagnostic test.  Of course sometimes my new diagnostic fails but I have
> > data from my 'gold standard'
> >
> > To me this really starts moving towards classification but I cannot seem
> to
> > find the appropriate calculations.
> >
> > Can someone point me to some web resources to determine the appropriate
> > method to be able to deal with the NULLs ?  Resources within the medical
> > realm would be better (because the rest of the folks would understand
> them
> > better) but not required.
> >
> > --
> > - Don
> >
> > Donald Catanzaro PhD
> > dgcatanzaro@gmail.com
> > 16144 Sigmond Lane
> > Lowell, AR 72745
> > 479-751-3616
> >
> >         [[alternative HTML version deleted]]
> >
> > ______________________________________________
> > R-help@r-project.org mailing list
> > https://stat.ethz.ch/mailman/listinfo/r-help
> > PLEASE do read the posting guide
> http://www.R-project.org/posting-guide.html
> > and provide commented, minimal, self-contained, reproducible code.
>
>
>
> --
>
> Bert Gunter
> Genentech Nonclinical Biostatistics
>
> Internal Contact Info:
> Phone: 467-7374
> Website:
>
> http://pharmadevelopment.roche.com/index/pdb/pdb-functional-groups/pdb-biostatistics/pdb-ncb-home.htm
>



-- 
- Don

Donald Catanzaro PhD
dgcatanzaro@gmail.com
16144 Sigmond Lane
Lowell, AR 72745
479-751-3616

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