I specifically wanted to do an adjusted covariable analysis and I want
incorporate genetic information in that. The language tossed around is just
to do an 'adjusted analysis', but I am not certain if this is common
terminology as I am relatively new to biostatistics. Perhaps I did not
express myself well enough, so I apologize. I justed wanted to know if R had
some packages available that could help me with this because I have been
having trouble finding it.

Thank you,

Ana


On Wed, May 18, 2011 at 3:14 PM, Frank Harrell <f.harrell@vanderbilt.edu>wrote:

> First of all, use the correct terminology for the statistical method.
>
> It is not productive to identify 'significant' genes unless you use quite
> complex methods.  This kind of endeavor would take at least 6 statistics
> courses in order to be successful.
> Frank
>
> Anamaria Crisan wrote:
> >
> > Hello,
> >
> > I would like some help figuring out how to run
> > Covariable Logistic Regression in R. I've been searching for a while on
> > how
> > to get this done in R (I have had the luck previously of using a software
> > package that just does it) and I am coming up empty handed. Any
> experience
> > or insights would be greatly appreciated.
> >
> > There is a package that does do exactly what I want, with the exception
> > that
> > it requires very specific data input, it is called :  mbmdr. My input
> > consists of various clinical variables measured from patients  as well as
> > expression data from various genes. What I would like to do is identify
> > significant genes while considering their interactions with the various
> > clinical variables.
> >
> >
> > Thank you,
> >
> > Ana
> >
> >       [[alternative HTML version deleted]]
> >
> > ______________________________________________
> > R-help@r-project.org mailing list
> > https://stat.ethz.ch/mailman/listinfo/r-help
> > PLEASE do read the posting guide
> > http://www.R-project.org/posting-guide.html
> > and provide commented, minimal, self-contained, reproducible code.
> >
>
>
> -----
> Frank Harrell
> Department of Biostatistics, Vanderbilt University
> --
> View this message in context:
> http://r.789695.n4.nabble.com/Covariable-Logistic-Regression-In-R-tp3533886p3534114.html
> Sent from the R help mailing list archive at Nabble.com.
>
> ______________________________________________
> R-help@r-project.org mailing list
> https://stat.ethz.ch/mailman/listinfo/r-help
> PLEASE do read the posting guide
> http://www.R-project.org/posting-guide.html
> and provide commented, minimal, self-contained, reproducible code.
>



-- 
Anamaria Crisan
Medical Genomics Research Associate
GenomeDx Biosciences Inc. | 201-1595 W. 3rd Ave, Vancouver, BC V6J 1J8
Off: 604-569-0072 | Fax: 866-505-5161
ana <http://goog_1098469627>@genomedx.com
www.genomedx.com

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