Dear all,

 

I would like to simulate a study in which the prevalence of an event is 1%
(p = 0.01), and the risk of the event is associated with two risk factors:
x1 and x2.  The odds ratio per standard deviation increase in x1 is 1.8 (95%
CI: 1.1 to 2.8), and the odds ratio for x2 being present is 2.1 (1.8 - 3.1).
x1 is a continuous variable with normal distribution (mean = 1.0, SD=0.10).
x2 is a categorical variable (with two values 0 and 1), and the prevalence
of x2=1 is around 10%.  

 

I have looked at the codes given in Design package, but I am not sure how to
simulate the prevalence.  Any help is highly appreciated.

Regard,

 

Nguyen

 

____________________________ 
Nguyen Dinh Nguyen

Bone and Mineral Research Program 
Garvan Institute of Medical Research 
St Vincent's Hospital 
384 Victoria Street, Darlinghurst 
Sydney, NSW 2010 
Australia 
Tel; 61-2-9295 8274 
Fax: 61-2-9295 8241 
E-mail: n.nguyen@garvan.org.au  

 

 

 


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