 hi,
I applied coxph to my matrix of 300 samples and 215 variables and got the following error

Error in fitter(X, Y, strats, offset, init, control, weights = weights,  :
        NA/NaN/Inf in foreign function call (arg 6)
In addition: Warning message:
Ran out of iterations and did not converge in: fitter(X, Y, strats, offset, init, control, weights = weights,

26% of time data is censored and here is the result of density of the matrix

       x                y
 Min.   :-6.943   Min.   :-5.258e-18
 1st Qu.:-4.086   1st Qu.: 2.341e-04
 Median :-1.228   Median : 4.584e-03
 Mean   :-1.228   Mean   : 8.740e-02
 3rd Qu.: 1.630   3rd Qu.: 5.857e-02
 Max.   :      4.487   Max.   : 7.099e-01
------------------------------------------------------------------------------
in another trial of the same matrix, the number of var is reduced to 188. the variables were normalized (mean = 0 and standard dev = 1 for each variable) and here is the result of density
       x                 y
 Min.   :-8.1532   Min.   :4.571e-16
 1st Qu.:-4.3334   1st Qu.:1.043e-04
 Median :-0.5136   Median :1.102e-03
 Mean   :-0.5136   Mean   :6.538e-02
 3rd Qu.: 3.3062   3rd Qu.:5.373e-02
 Max.   : 7.1260   Max.   :4.337e-01

I get still the warning
 Warning message:
 Ran out of iterations and did not converge in: fitter(X, Y, strats, offset,  init,     control, weights = weights,
but not error in fitter ....

the number of iterations is 20 and didn't converge. saw from coefficient values and their p-value

Why do I get this message? 

Look forward to your reply

carol
 
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