Hello,
I am planning a study with the main point to evaluate the interaction of two treatments, 
but for ethical reasons one cell is empty, that with patients receaving no treatment at all

                                                                    
                                                                    
                            Treatment B
                                  
                                                                    
                                                                    
+
-

Treatment A
+
a
b

                                                                    
-
c
-------


I am looking for functions in R to estimate the sample size and/or to conduct the 
analysis. I have just found an article from Byar in Statistics in Medicine for a 2^3 
incomplete factorial design, but I would like not to discover again the wheel..
TIA
dr. Giovanni Parrinello
Section of Medical Statistics
Department of Biosciences
University of Brescia
25127 Viale Europa, 11
Brescia Italy
Tel: +390303717528
Fax: +390303701157



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