[R] [R-pkgs] simplePHENOTYPES: SIMulation of Pleiotropic, Linked and Epistatic PHENOTYPES

[Bonfim Fernandes, Samuel]

Hi All,

I hope this message finds you well.
I have developed the simplePHENOTYPES package to simulate single and multiple (correlated) traits in a wide range of scenarios, including additive, dominance, and epistatic (AxA) models.
The newest version, simplePHENOTYPES v1.2.4, which has just been released on CRAN, has substantial improvements compared to the previous one.

Some of the new features include:
- Options for using VCF, plink bed/ped files, GDS, HapMap, and Numeric as input files.
- Implementation of two types of spurious pleiotropy simulation (“direct" and "indirect").
- Simulation of residual correlation among traits.

Please check it our here:
https://cran.r-project.org/package=simplePHENOTYPES
Vignettes for the most common scenarios one would want to simulate may be found here:
https://cran.r-project.org/web/packages/simplePHENOTYPES/vignettes/simplePHENOTYPES.html

Best regards,
Samuel Fernandes

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