[R] Clinical significance - Equivalence test

[Jim Lemon]

On 03/28/2014 12:53 AM, Manuel Carona wrote:
> Hi,
>
> I have implemented a therapeutic intervention on two groups (one is a
> control group) and tested them in two moments using some assessment
> tools (with normative data). Now I want to compare the experimental
> group with the control group using clinical equivalence testing. To do
> this I need to specify a range of closeness (One for each assessment
> tool according to the specificity of this same tool) and do two
> one-tailed tests to test if the two groups are considered clinically
> equivalent in the first moment and on the end I want to compare the
> experimental group with the normative data (Here I have to add the mean
> and standard deviation of the normative sample because I don't have the
> normative sample).
>
> I know that R has a package named equivalence but I don't know how to do
> this kind of calculations with it. Is it even possible with the actual
> packages?
>
Hi Manuel,
Are you looking for the Jacobsen-Truax clinical significance tests? Have 
a look at the clinsig package.

Jim