[R] Interperting results of glmnet and coxph plot, Brier score and Harrel's C-Index - am I doing something wrong ???

Terry Therneau therneau at mayo.edu
Mon Sep 30 16:30:01 CEST 2013


To elaborate on Frank's response, the analysis plan of
   1. Look at the data and select "important" variables
   2. Put that truncated list into your favorite statistic procedure
   3. Ask - are the p-values (c-statistic, coefficients, .....) reliable?

is a very old plan.  The answer to the last question is always "NO".
The traditional step 1 involved graphs and t-tests, but replacing it by something modern 
does not change the overall outcome.

Terry T



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