[R] R-help Digest, Vol 124, Issue 22

David Duffy David.Duffy at qimr.edu.au
Sat Jun 22 05:09:44 CEST 2013

"Vallejo, Roger" <Roger.Vallejo at ARS.USDA.GOV> asked:

> I would like to know if we can estimate Rg between two binary traits
> (disease status: alive vs. dead) with the R package.
> My data: we have 100 full-sib (FS) families,
> and two random samples (each with n= 200 FS fish) from each FS family
> were evaluated for disease resistance to two different bacterial
> diseases, separately. Both traits are not recorded in the same
> individual; both traits are recorded in different full-sibs from a FS
> family.

Yes. Check out http://glmm.wikidot.com/ and the R-sig-mixed-models list. 
MCMCglmm is the package most explicitly for multivariate
genetic analysis, but given you have only full sibs, there are a quite a 
few choices.

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