[R] Need to replicate Boltzman Signmodial Curve fit from Graph Pad
R. Michael Weylandt
michael.weylandt at gmail.com
Tue Apr 23 18:45:51 CEST 2013
On Tue, Apr 23, 2013 at 3:55 PM, J J <rnoobier at gmail.com> wrote:
> Hello useRs (please don't kill me),
> I've fairly new to R having only a few months of playing around with R.
> What little I've learned has been extremely useful.
> If someone could point me as to how to replicate the Boltzman Sigmodial
> curve fit as provided by Graphpad software I'd be eternally grateful.
> Where we currently use Graphpad for only this one function,its seems
> highly inefficient for a $100 piece of software to be used for only one
> function (which isn't nearly as bad as the company's pandemic reliance on
> Excel for nearly everything else).
> so anyway, what I'd normally do is take a set of data like this:
> pH counts 3.8 968 5.0 1347 5.8 2867 6.6 9203 7.0 15817 7.4 20297 8.2
> 31916 9.2 35756
> then fit this to a Boltzman sigmodial in Graphpad. Graphpad spits out a
> much longer set of vectors and also information about v50 and confidence
> intervals etc (if anyone is familiar with that software). This is what i'd
> like to replicate.
> It might be that I just don't know what i'm doing,so feel free to call me
> an idiot but any help is greatly appreciated!
Being unfamiliar with the problem domain, I'd imagine that nls() would
probably be what you're looking for. Does
seem promising? If so, we can help you get started.
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