[R] lme random slope results the same as random slope and intercept model

ONKELINX, Thierry Thierry.ONKELINX at inbo.be
Tue Jun 12 17:14:29 CEST 2012


Dear John,

R-sig-mixed-models is a better list for this kind of questions.

It looks like the model finds no evidence for a random slope. Notice the very small variance of the random slope. In the model without random intercept, the random slope tries to mimic the effect of a random intercept.

Best regards,

Thierry

ir. Thierry Onkelinx
Instituut voor natuur- en bosonderzoek / Research Institute for Nature and Forest
team Biometrie & Kwaliteitszorg / team Biometrics & Quality Assurance
Kliniekstraat 25
1070 Anderlecht
Belgium
+ 32 2 525 02 51
+ 32 54 43 61 85
Thierry.Onkelinx op inbo.be
www.inbo.be

To call in the statistician after the experiment is done may be no more than asking him to perform a post-mortem examination: he may be able to say what the experiment died of.
~ Sir Ronald Aylmer Fisher

The plural of anecdote is not data.
~ Roger Brinner

The combination of some data and an aching desire for an answer does not ensure that a reasonable answer can be extracted from a given body of data.
~ John Tukey


-----Oorspronkelijk bericht-----
Van: r-help-bounces op r-project.org [mailto:r-help-bounces op r-project.org] Namens John Sorkin
Verzonden: dinsdag 12 juni 2012 16:52
Aan: r-help op r-project.org
Onderwerp: [R] lme random slope results the same as random slope and intercept model

R 2.15.0
Windows XP



Can someone help me understand why a random intercept model gives the same results as the random intercept and slope models?

I am rather surprised by the results I am getting from lme. I am running three models
(1) random intercept
     fitRI   <- lme(echogen~time,random=~  1     |subject,data=repeatdata,na.action=na.omit)
(2) random slope
>    fitRT   <- lme(echogen~time,random=~ -1+time|subject,data=repeatdata,na.action=na.omit)
(3) random intercept and slope.
     fitRIRT <- lme(echogen~time,random=~  1+time|subject,data=repeatdata,na.action=na.omit)
The results of the (1) random intercept model are different from the (2) random slope model,not a surprise.
The results of the (1) random intercept model and the (3) random intercept and slope models are exactly the same, a surprise!

Below I copy the results for each model. Further below I give all my output.

RESULTS FROM EACH MODEL
(1) Random intercept results:
Random effects:
 Formula: ~1 | subject
        (Intercept) Residual
StdDev:     19.1751 10.44601

Fixed effects: echogen ~ time
               Value Std.Error DF   t-value p-value
(Intercept) 64.54864  4.258235 32 15.158545  0.0000
time         0.35795  0.227080 32  1.576307  0.1248
 Correlation:
     (Intr)
time -0.242


(2) Random slope results
Random effects:
 Formula: ~-1 + time | subject
             time Residual
StdDev: 0.6014915 19.63638

Fixed effects: echogen ~ time
               Value Std.Error DF   t-value p-value
(Intercept) 65.03691  3.494160 32 18.613032  0.0000
time         0.22688  0.467306 32  0.485503  0.6306
 Correlation:
     (Intr)
time -0.625


(3) Random intercept and slope results
Random effects:
 Formula: ~1 + time | subject
 Structure: General positive-definite, Log-Cholesky parametrization
            StdDev       Corr
(Intercept) 1.917511e+01 (Intr)
time        2.032072e-04 0
Residual    1.044601e+01

Fixed effects: echogen ~ time
               Value Std.Error DF   t-value p-value
(Intercept) 64.54864  4.258235 32 15.158543  0.0000
time         0.35795  0.227080 32  1.576307  0.1248
 Correlation:
     (Intr)
time -0.242






COMPLETE OUTPUT
> repeatdata
    subject time value echogen
1         1    1    22      63
2         1    3    40      60
3         1   NA    NA      NA
4         1   NA    NA      NA
5         1   NA    NA      NA
6         2    1    39      19
7         2   NA    NA      NA
8         2   NA    NA      NA
9         2   NA    NA      NA
10        2   NA    NA      NA
11        3    1    47      76
12        3    6    43      82
13        3   NA    NA      NA
14        3   NA    NA      NA
15        3   NA    NA      NA
16        4    1    44      44
17        4    3    50      50
18        4    7    67      67
19        4   21    39      39
20        4   NA    NA      NA
21        5    1    42      58
22        5    3    60      78
23        5    7    86      85
24        5   19    56      60
25        5   35    39      84
26        6    1    57      67
27        6   NA    NA      NA
28        6   NA    NA      NA
29        6   NA    NA      NA
30        6   NA    NA      NA
31        7    1    71      58
32        7    3    55      67
33        7   10    57      95
34        7   17    62      94
35        7   25    47      73
36        8    1    79     105
37        8   NA    NA      NA
38        8   NA    NA      NA
39        8   NA    NA      NA
40        8   NA    NA      NA
41        9    1    60      70
42        9    3    64      62
43        9    9    68      65
44        9   NA    NA      NA
45        9   NA    NA      NA
46       10    1    47      75
47       10    3    49      73
48       10    9    46      70
49       10   17    48      70
50       10   NA    NA      NA
51       11    1    57      97
52       11    6    75     108
53       11   NA    NA      NA
54       11   NA    NA      NA
55       11   NA    NA      NA
56       12    1    85     116
57       12    3    77     110
58       12   NA    NA      NA
59       12   NA    NA      NA
60       12   NA    NA      NA
61       13    1    34      51
62       13   NA    NA      NA
63       13   NA    NA      NA
64       13   NA    NA      NA
65       13   NA    NA      NA
66       14    1    30      59
67       14    3    NA      NA
68       14   NA    NA      NA
69       14   NA    NA      NA
70       14   NA    NA      NA
71       15    1    42      47
72       15    3    50      62
73       15   11    33      75
74       15   NA    NA      NA
75       15   NA    NA      NA
76       16    1    NA      83
77       16    7    NA      88
78       16   13    NA      74
79       16   NA    NA      NA
80       16   NA    NA      NA
81       17    1    NA      51
82       17    7    NA      62
83       17   NA    NA      NA
84       17   NA    NA      NA
85       17   NA    NA      NA
86       18    1    NA      39
87       18    7    NA      44
88       18   NA    NA      NA
89       18   NA    NA      NA
90       18   NA    NA      NA
91       19    1    NA      45
92       19    7    NA      56
93       19   14    NA      NA
94       19   NA    NA      NA
95       19   NA    NA      NA
96       20    1    NA      45
97       20    7    NA      57
98       20   NA    NA      NA
99       20   NA    NA      NA
100      20   NA    NA      NA
101      21    1    NA      80
102      21   NA    NA      NA
103      21   NA    NA      NA
104      21   NA    NA      NA
105      21   NA    NA      NA
106      22    1    NA      42
107      22    7    NA      33
108      22   14    NA      36
109      22   21    NA      NA
110      22   NA    NA      NA
111      23    1    NA      69
112      23    7    NA      68
113      23   NA    NA      NA
114      23   NA    NA      NA
115      23   NA    NA      NA
116      24    1    NA      48
117      24    6    NA      58
118      24   14    NA      82
119      24   NA    NA      NA
120      24   NA    NA      NA
121      25    1    NA      67
122      25   NA    NA      NA
123      25   NA    NA      NA
124      25   NA    NA      NA
125      25   NA    NA      NA
>
> library(nlme)
> fitRI   <- lme(echogen~time,random=~  1     |subject,data=repeatdata,na.action=na.omit)
> summary(fitRI)
Linear mixed-effects model fit by REML
 Data: repeatdata
      AIC      BIC    logLik
  491.097 499.1984 -241.5485

Random effects:
 Formula: ~1 | subject
        (Intercept) Residual
StdDev:     19.1751 10.44601

Fixed effects: echogen ~ time
               Value Std.Error DF   t-value p-value
(Intercept) 64.54864  4.258235 32 15.158545  0.0000
time         0.35795  0.227080 32  1.576307  0.1248
 Correlation:
     (Intr)
time -0.242

Standardized Within-Group Residuals:
        Min          Q1         Med          Q3         Max
-1.61362748 -0.52710871  0.02948022  0.41793307  1.77340062

Number of Observations: 58
Number of Groups: 25
>
> fitRT   <- lme(echogen~time,random=~ -1+time|subject,data=repeatdata,na.action=na.omit)
> summary(fitRT)
Linear mixed-effects model fit by REML
 Data: repeatdata
       AIC      BIC    logLik
  515.2225 523.3239 -253.6112

Random effects:
 Formula: ~-1 + time | subject
             time Residual
StdDev: 0.6014915 19.63638

Fixed effects: echogen ~ time
               Value Std.Error DF   t-value p-value
(Intercept) 65.03691  3.494160 32 18.613032  0.0000
time         0.22688  0.467306 32  0.485503  0.6306
 Correlation:
     (Intr)
time -0.625

Standardized Within-Group Residuals:
        Min          Q1         Med          Q3         Max
-2.35381603 -0.69490411 -0.04299361  0.52973023  2.57509584

Number of Observations: 58
Number of Groups: 25
>
> fitRIRT <- lme(echogen~time,random=~
> 1+time|subject,data=repeatdata,na.action=na.omit)
> summary(fitRIRT)
Linear mixed-effects model fit by REML
 Data: repeatdata
      AIC      BIC    logLik
  495.097 507.2491 -241.5485

Random effects:
 Formula: ~1 + time | subject
 Structure: General positive-definite, Log-Cholesky parametrization
            StdDev       Corr
(Intercept) 1.917511e+01 (Intr)
time        2.032072e-04 0
Residual    1.044601e+01

Fixed effects: echogen ~ time
               Value Std.Error DF   t-value p-value
(Intercept) 64.54864  4.258235 32 15.158543  0.0000
time         0.35795  0.227080 32  1.576307  0.1248
 Correlation:
     (Intr)
time -0.242

Standardized Within-Group Residuals:
        Min          Q1         Med          Q3         Max
-1.61362755 -0.52710871  0.02948008  0.41793322  1.77340082

Number of Observations: 58
Number of Groups: 25
>




John David Sorkin M.D., Ph.D.
Chief, Biostatistics and Informatics
University of Maryland School of Medicine Division of Gerontology Baltimore VA Medical Center
10 North Greene Street
GRECC (BT/18/GR)
Baltimore, MD 21201-1524
(Phone) 410-605-7119
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