[R] Please help....normalization by the median of some control genes

arun smartpink111 at yahoo.com
Fri Aug 24 01:52:55 CEST 2012


HI,

You could try:
limma package: normalizeWithinArrays()
A.K.



----- Original Message -----
From: David Lyon <david_lyon3 at yahoo.com>
To: "r-help at r-project.org" <r-help at r-project.org>
Cc: 
Sent: Thursday, August 23, 2012 8:37 AM
Subject: [R] Please help....normalization by the median of some control genes

Can someone show me some code to do normalization by the median of some control genes for the example below?

Many Many Thanks in advance



This strategy selects a subset of genes (called “control genes”) and makes the median of their data distribution similar across arrays.

        id1    id2    id3
control1    0.8    0.7    0.6
control2    0.6    0.2    0.4
probe1        0.3    0.2    0.5
probe2        0.4    0.9    0.7
probe3        0.6    0.7    0.4


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