[R] how to compare C-index in Cox model

frank.chiang frank.chiang86 at gmail.com
Wed Apr 11 10:12:15 CEST 2012

Dear List,

If I calculate the C-index after 10-fold cross-validation based on Cox
model, which statistic test 

should I used to compare two C-statistc values.I means I use
cross-validation to obtain a predictive 

probability for each individual, then combine all the probabilities to
calculate the C-index.If I get 

two C-index values(0.73 vs. 0.80) based on two different model, then how to
test the difference is significant.

For the C-index values got from a single dataset, we may use bootstrap to
get the standard error, and 

use wald test to measure whether they are significant different,but if
c-index got from cross-

validation,whether I can still use this method to compare them.

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