[R] Multiple events Cox's model and proportional hazards

natalie.vanzuydam nvanzuydam at gmail.com
Thu Sep 1 10:34:45 CEST 2011


I am using the survival package to perform a Cox's regression analysis on
multiple events of myocardial infarctions.  I have been using the Andersen
and Gill model: 

I was just wondering if this model should satisfy proportional hazards
assumptions.  I have run  the cox.zph function and the age parameter
violates the proportional hazards?  What would be the best way to construct
this model.  Should I include time dependent covariates?


Natalie Van Zuydam

PhD Student
University of Dundee
nvanzuydam at dundee.ac.uk
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