[R] Multilevel Survival Analysis - Cox PH Model
ross.dunne at tcd.ie
Sat Jul 2 12:52:44 CEST 2011
There is indeed right censoring, but I obviously didn't explain it very well.
Patients are either fully oriented or not (1 or 2) after an hour. If they're
not, then the data is right censored.
However, I don't feel that "coxme" is overkill at all, as I may also have to
account for repeated COURSES of treatments on the same individiual, so the
data would be structured as follows: TREATMENTS repeated within COURSES
repeated within PATIENTS.
However, I may need a little help later specifying the model technically in
What would the random effects bit of the formula look like? At the moment
mycoxme<-coxme(mysurv~SEX + (1|MRN))
would a correct specification for the nested data be:
mycoxme<-coxme(mysurv~SEX + (1|MRN|COURSE))
Then of course we have the added issue that treatments are ordered.... so is
there a "Frailty" model that can account for that I wonder?
Thanks for all your help.
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