[R] OT: Is randomization for targeted cancer therapies ethical?

Bert Gunter gunter.berton at gene.com
Mon Sep 20 19:31:00 CEST 2010


Hi Folks:

**Off Topic**

Those interested in clinical trials may find the following of interest:

http://www.nytimes.com/2010/09/19/health/research/19trial.html

It concerns the ethicality of randomizing those with life-threatening
disease to relatively ineffective SOC when new "biologically targeted"
therapies "appear" to be more effective. While the context may be new,
the debate, itself, is not: Tukey wrote (or maybe it was talked -- I
can't remember for sure) about this about 30 years ago. I'm sure many
other also have done so.

Cheers,

Bert
-- 
Bert Gunter
Genentech Nonclinical Biostatistics



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