[R] Survival Analysis Daily Time-Varying Covariate but Event Time Unknown

smm7aa smm7aa at virginia.edu
Thu Sep 16 18:14:19 CEST 2010


Help!

I am unsure if I can analyze data from the following experiment.

Fish were placed in a tank at (t=0)
Measurements of Carbon Dioxide were taken each day for 120 days (t=0,...120)
A few fish were then randomly pulled out of the tank at different days,
killed and examined for the presence of a disease
T= time of examination in days from start (i.e. 85th day), E = 0/1 for
nonevent/event

My problem has been linking all the Carbon Dioxide measurements up to the
day of examination and trying to create a survival object.

I have considered interval censoring with right censored for fish without
disease and then left censored for fish with the disease, but i really
cannot structure the data or intuitively figure out how to incorporate the
daily Carbon Dioxide values up until day of examination.

The end goal to to predict an event based on Carbon Dioxide levels

Thank you for help or redirection.

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