[R] Piece-wise continuous regression with one knot

John Sorkin jsorkin at grecc.umaryland.edu
Thu Dec 23 15:03:46 CET 2010

Windows Vista
R 2.10 - I know it is old, I will update later today.

How might I perform a piece-wise linear regression where two linear segments are separated by a single knot? In addition to estimating the slopes of the two segments (or the slope in one segment and the difference between the slope of the first and second segment), I would like the analysis to select the optimum knot. My first analysis will contain a single dependent and a single independent variables. Subsequent analyses will add additional independent variables to determine the effect on the results of adjusting for potential confounding.
Thank you,

John David Sorkin M.D., Ph.D.
Chief, Biostatistics and Informatics
University of Maryland School of Medicine Division of Gerontology
Baltimore VA Medical Center
10 North Greene Street
Baltimore, MD 21201-1524
(Phone) 410-605-7119
(Fax) 410-605-7913 (Please call phone number above prior to faxing)

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