[R] Package implementing unconditional tests for comparing two binomials

Thorsten Raff t.raff at med2.uni-kiel.de
Tue Sep 16 11:18:54 CEST 2008


I am looking for a package implementing unconditional tests for comparing two 
binomials (Barnard's test or derivatives). As I am looking for rare genotypes 
within my groups, my number of subjects in one of the cells of the 2x2 table 
is often 2-4 resulting in a too conservative result by Fisher's exact test due 
to the discrete sample space of the test statistic. As I want to use this as a 
kind of filter for further investigations I am really interested in the 
additional power for 2x2 tables.

Any help or suggestions are really appreciated
Thank you very much


Thorsten Raff
2nd Medical Department,
University Hospital Schleswig-Holstein, Campus Kiel
Chemnitzstraße 33
24116 Kiel

phone: +49 431 1697-5234
fax:   +49 431 1697-1264

email: t.raff<at>med2.uni-kiel.de
web:   www.uk-s-h.de

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